Comparison of the Effects of Propofol and Midazolam Sedation on Post-dural Puncture Headache
| Author | Mohammadtaghi Khodadadi | en |
| Author | Fatemeh Pouladkhay | en |
| Author | Alireza Talaie | en |
| Author | Maryam Taghavi | en |
| Author | Mousa Sajjadi | en |
| Author | Reza Mehmandoust | en |
| Orcid | Mohammadtaghi Khodadadi [0000-0002-8932-2713] | en |
| Orcid | Fatemeh Pouladkhay [0000-0002-6808-7216] | en |
| Orcid | Alireza Talaie [0000-0002-3928-873X] | en |
| Orcid | Mousa Sajjadi [0000-0002-5449-9113] | en |
| Orcid | Reza Mehmandoust [0009-0009-4521-5375] | en |
| Issued Date | 2023-09-30 | en |
| Abstract | Background: Post-dural puncture headache (PDPH) is a common side effect after spinal anesthesia. Objectives: This study aimed to compare the sedative dose of propofol and midazolam in reducing headaches after spinal anesthesia. Methods: In order to conduct this study, 80 candidates for spinal anesthesia were divided into two groups, A and B. Both groups received spinal anesthesia with marcaine. In group A, propofol was infused slowly at a dose of 30 µg per minute, and in group B, 1 mg midazolam was injected intravenously. In the two groups, the incidence and intensity of headaches were measured using the VAS pain scale. Data were analyzed using Mann-Whitney and t-tests at a significance level of 0.05. Results: In this study, 65% (52) were male and 35% (28) were female. There was no significant difference between the two groups in terms of demographic information (P > 0.05). In the propofol group, the incidence and severity of headaches were significantly lower than in the midazolam group (P < 0.01). Conclusions: This study's results indicated that administering low-dose propofol as a sedative during spinal anesthesia may be more effective in reducing PDPH than midazolam. | en |
| DOI | https://doi.org/10.5812/amh-141446 | en |
| Keyword | Midazolam | en |
| Keyword | Propofol | en |
| Keyword | Spinal | en |
| Keyword | Headache | en |
| Keyword | PDPH | en |
| Publisher | Brieflands | en |
| Title | Comparison of the Effects of Propofol and Midazolam Sedation on Post-dural Puncture Headache | en |
| Type | Research Article | en |
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