Annals of Military and Health Sciences Research
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Annals of Military and Health Sciences Research ( AMHSR) is a peer-reviewed middle-eastern medical journal publishing in all clinical and theoretical aspects of medicine scientific reports of original research in such areas as medical economic policy, medical ethics, and managing healthcare systems are also considered for publication. AMHSR is published quarterly and is the official journal of Aja University of Medical Sciences.
Its content includes original research, brief communication, expert and systematic reviews, case reports, case series, letter to the editor, and technical innovation with the aim of promoting new advances in the field and enhancing standards of professional practice. Also, reviews of newly published books and articles are welcomed. In addition, historical articles which discuss the remarkable history of medicine all over the world, especially the Persian and Egyptian medicine, are of special merit.
Peer Review Policy:
1) Double-Blind Peer Review System
2) Open Peer Review (since Aug 2019), Show List of All Published Reviewers' Comments
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Recent Submissions
- ItemThe Effect of Endurance Training with Crocin Consumption on the Levels of AMPK and NRF1 Gene Expression in the Soleus Muscles of Diabetic Rats(Brieflands, 2021-06-30) Abdolnabi Peyravi; Hashem Nayeri; Nasrin Yazdanpanahi; Seyed Ali HosseiniBackground: Exercise training and crocin, as a herbal antioxidant, help improve metabolism and insulin sensitivity in type 2 diabetes mellitus (T2D). AMP-activated protein kinase (AMPK) and nuclear respiratory factor 1 (NRF1) involve in the mitochondrial biogenesis pathway and diabetes control. Objective: This study aimed to investigate the effects of high-intensity interval training (HIIT), and low intensity continued training (LICT) in combination with crocin consumption on AMPK and NRF1 gene expression in the muscle tissue of diabetic rats. Methods: In this experimental study, 56 adult rats were divided into eight groups (n = 7), including diabetic (crocin utilization, HIIT, LICT, HIIT with crocin, LICT with crocin, control, sham groups) and healthy control group. The HIIT and LICT groups performed five sessions of training per week for eight weeks, and the crocin consumption groups received 25 mg/kg of crocin daily for eight weeks. Moreover, AMPK and NRF1 genes expression levels were evaluated in different groups using real-time polymerase chain reaction (RT-PCR). Results: According to our results, while induction of diabetes significantly decreased the levels of NRF1 and AMPK gene expression (P ≤ 0.05), training and crocin consumption significantly increased the levels of AMPK and NRF1 gene expression (P ≤ 0.05). Conclusions: It appears that crocin consumption along with HIIT improves diabetes symptoms through AMPK and NRF1 mechanism in diabetic rats.
- ItemApplication of L-Arginine as nitric oxide inducer and Indomethacin as prostaglandin inhibitor in Balb/c mice infected with Leishmania major MRHO/IR/75/ER(Brieflands, 2013-03-31) Fatemeh Ghasemi; Hossein NahrevanianBackground: Leishmaniasis is one of the health problems in. This study is designed to inhibit PG production by Indomethacin and induce NO by L- Arginine precursor in L. major infected Balb/c mice.
- ItemSerum and Stimulated Saliva C-reactive Protein Changes in Altitude Chamber(Brieflands, 2017-09-30) Iraj Mirzaii-Dizgah; Aboulfazl KhademiObjectives: The object of the research was to examine stimulated saliva and serum C-reactive protein (hs-CRP) prior and following the experience of hypobaric hypoxia process (EHHP) in an altitude chamber in aviators. Methods: A total of 40 healthy aircrew (age: 31.8 ± 6.0 years; BMI: 25.6 ± 2.7 Kg/cm2) experienced hypobaric chamber. Hs-CRP levels were assayed in stimulated whole saliva and serum before and after intervention by the ELISA method and were statistically analyzed by the paired student’s t test. Results: Mean serum hs-CRP concentration was significantly increased following intervention (before: 1.78 ± 0.33 µg/mL versus after: 2.58 ± 0.45 µg/mL) (p = 0.02). Stimulated saliva hs-CRP level was also significantly higher following EHHP (1.71 ± 0.17 ng/mL) compared to before experiencing it (0.79 ± 0.12 ng/mL, P = 0.007). Conclusions: It seems that the salivary and serum levels of hs-CRP rise following the experience of hypobaric hypoxia process.
- ItemPenetrating Heart Injury: a case report(Brieflands, 2013-06-30) Ali Karbalaikhani; Azita shishegar; Salman DehkhodaPenetrating heart trauma is usually life threatening and it usually requires emergent surgical exploration. Pre-hospital mortality rate and death on arrival is very high. We describe a case of 42 years old man, suffering from stab wound to the fifth left intercostal space that was in shock and severe respiratory distress during admission in emergency room.
- ItemHealing Effects of Iranian Dwarf Elder on Full-thickness Epidermal Thermal Injury in Wistar Rats(Brieflands, 2021-12-31) Hosein Mohamadi Haftador; Parisa Ramhormozi; Mitra Yousefpour; Ali Sobhanizadeh; Laya GhahariBackground: Wound healing is a physiologic process that cells and tissues react when the skin is exposed to thermal injury. The inflammatory process has essential effects on wound healing that includes coordination between immunological and biological responses. Chemical and herbal medicines are locally or systemically administrated to help wound healing. Herbal medicines have become more prevalent in recent years due to fewer side effects. Dwarf elder is used to treating inflammation and has been reported to possess antibacterial and antioxidant activities. This plant is also effective against burns, wounds, eczema, and infection. Objectives: In this study, we evaluated the topical application of dwarf elder on full-thickness epidermal thermal wounds in Wistar rats. Methods: Thirty adult male Wistar rats of about 300 g were used. The rats were randomly divided into three groups: Control group, vehicle group treated with an ointment base, and treatment group treated with elder ointment 10%. The animals were anesthetized and were created burn wounds with an area of 1 cm2 using the Meyer method. After 21 days, the wounds were photographed with a Canon camera. The wound area and healing degree were calculated. Slides were stained with H&E and examined by light microscopy and GraphPad Prism software. Data were analyzed by SPSS software using ANOVA and Tukey’s test. The significance level was considered at P < 0.05. Results: The wound area on the 21st day was significantly lower in the treatment group than in the control and vehicle groups. The epithelium thickness (μm) was significantly higher in the treatment group than in the control and vehicle groups. The blood vessels were significantly higher in the treatment group than in the other groups. Conclusions: The study showed that elder extract could be an effective remedy to repair and heal thermal injury and burn wounds.
- ItemEpidemiologic profile of shigellosis among Iranian military personnel: a retrospective study in the Army(Brieflands, 2014-06-30) Arasb Dabbagh-Moghaddam; Elnaz Tabibian; Mahtab Noorifard; Seyed Javad Hosseini-Shokouh; Shahram Rahimi Dehgolan; Mohsen TootoonchianMaterials and Methods: The data was gathered from archived reports of Iran’s Army at AJA University of Medical Sciences. All military personnel with confirmed diagnosis of shigellosis reported by the Army physicians were included in the study. Data analysis was done by appropriate statistical functions using STATA software.
- ItemAssessment of Bactaslyde media in diagnosis of Salmonella in water and foods in comparison with standard method in order to use in crisis(Brieflands, 2013-06-30) Hooman Motlagh; Hamidreza Tavakoli; Arasb Dabbagh Moghaddam; Narjes Cheraghi; Hesameddin AkbareinBackground: Salmonellas are responsible for more than 40 percent of foodborne diseases in the world. Today, rapid diagnostic methods are essential for detecting these organisms in food and water especially in crisis. The aim of this study was to assess the Bactaslyde media usability in detection of salmonella and compare it with standard culture method.
- ItemChlamydia pneumoniae infection in patients with atherosclerotic plaques(Brieflands, 2013-09-03) Farhad Lahmi; Mohammad Rostami Nejad; Ehsan Nazemalhosseini Mojarad; Hossein Godarzi; Hossein Ahmadi; Hossein DabiriBackground: Previous studies showed that microbial infection such as Chlamydia pneumoniae is contributed to the development of atherosclerosis. This study evaluated the prevalence of C. pneumoniae in atherosclerotic plaques by PCR and immunofluorescence assay (IFA), and also it examined the correlation of disease severity and the presence of this bacterium. Materials and Methods: In this descriptive study sixty four specimens, thirty three plaques in case group and thirty one plaques in control group were assessed in Tehran University of Medical Sciences affiliated hospitals. The plaques was assessed by PCR nor IFA method. The data was analyzed by SPSS and t-test and fisher exact test was used. Results: Out of 33 case specimens, C. pneumoniae DNA and antigen were found in 6 (18%) and 7 (21%) of endarterectomy specimens, respectively. While none of control specimens was positive for C. pneumoniae either by neither PCR nor IFA method. Conclusion: Respect to remarkable presence of C. pneumoniae in atherosclerotic tissues and its absence in healthy vessels supports the hypothesis that C. pneumoniae may play an important role in the development of atherosclerosis, especially in regions where infection is frequent but the exact mechanisms for high prevalence of atherosclerotic vascular disease are not fully understood.
- ItemFauna and Seasonal Abundance of Domestic Mites as Respiratory Allergen in Three Military Areas, North of Iran in 2017 - 2018(Brieflands, 2019-06-30) Abdolazim Mortazavi Lahijani; Ramin Khaghani; Hamidreza Hajiqanbar; Seyed Shahram MirzamaniBackground: Domestic mites (DM) refer to all indoor mite species such as house dust mites (HDM) and some of the storage mites that are able to induce IgE-mediated sensitization. These microscopic mites are one of the most known risk factors of allergies and respiratory diseases in homes and other indoor places. Objectives: Considering the importance of DMs and lack of investigation on DMs in military areas of Iran, this study was designed to determine the fauna and biodiversity of DM in three military areas, North of Iran in 2017 - 2018. Methods: It was a cross-sectional study. Each military area was divided into three sampling zones (lieutenant dormitory, soldier dormitory and administrative place). In each sampling zone, seven places were randomly selected and dust samples were collected using a vacuum cleaner for 2 minutes from 1 m2 of the surface. After collection, samples were weighted separately. The mites were counted by a Stereo microscope, mounted in Hoyer’s medium, and identified by standard keys. The data were analyzed using statistical SPSS software version 17 and Microsoft Excel software version 2013 software. Results: A total of 648 dust samples were examined, in total 1043 mites were collected and identified that 741 mites were from six species of DM. The most abundant species were Dermatophagoides farinae (72.74%) and D. pteronyssinus (14.58%), and the less abundant species were Glycyphagus domesticus (0.94%) and Euroglyphusmaynei (0.54%). The most of DMs were found in the lieutenant dormitory (84.3%) and just 1.9% of DMs in the administrative place. The DMs were found almost throughout the year with the highest peaks in Jun. (11.1%), August (13.1%), September (14.7%), and October (11.1%), and the smallest peak in January (3.8%), February (4.2%), and March (3.2%). Conclusions: The results of this study show that all military areas are contaminated by DMs. Although the density of DM did not exceed the risk thresholds (10 mg mites/gram dust or 100 mites/gram dust), in the first and third lieutenant dormitories were near the risk threshold from January to November. Therefore, we suggest the preventive measures, particularly in the lieutenant dormitories, should be more effective than the past.
- ItemDesigning the evaluation framework for Clinical governance in IR Iran AJA Hospitals(Brieflands, 2013-12-31) Hamed Dehnavi; Nader Markazi-MoghadamBackground: Clinical Governance now selected as a model to improve the quality of health care services in hospitals of Iran. in recent years Army hospitals have made good progress in implementing this model, but over several years there is no appropriate tool for assessing clinical governance in the country. Materials and Methods: First, researcher studid books and paper related to the subject and do a search on the Internet and with content analysis provide the necessary framework then provided draft validate by the panel of experts with Lavashh method. After the questionnaire used to assess the four Army’s hospitals. Results: provided questionaire has eight areas; commitment to quality, clinical effectiveness, risk management, patient centerdness, staff management, information management, learning and clinical audit and has three dimention; infrasructure, deploy and results. Evaluation results show that hospitals in most areas are on average or closer to average Conclutions: The results show that a more coherent plan is needed to improve clinical governance conditions in armys hospitals.
- ItemIntestinal Parasitic Infections and Associated Factors Among Primary School Students in Tehran(Brieflands, 2023-12-31) Minoo Shaddel; Mohammad Hossein Hajali; Hamidreza Karbalaei-Musa; Behzad Narimany Eslami; Mohamad Mohsen HomayoniBackground: Parasitic infections in children can negatively impact their growth, health, nutrition status, and cognitive development. Objectives: This study aimed to investigate intestinal parasitic infection and its relationship with the nutritional status of primary school students in Tehran in 2020. Methods: The current study was conducted on 250 samples collected by the available sampling method from 2 selected residential settlements in Tehran. The samples were tested using both direct and formalin ether concentration (sedimentation) methods. The nutritional status of participants was evaluated using the Mini Nutritional Assessment (MNA) questionnaire. The data were analyzed by the χ2 test. A significant level was considered 0.05. Results: Of the 250 student samples surveyed, 45 exhibited parasitic infection. In terms of nutrition, 18 cases were malnourished, 212 cases were exposed to malnutrition, and 20 cases had normal nutrition. The frequency of parasitic infection was higher in malnourished students (P < 0.05). It was also higher in students whose parents' education levels (especially the mother) were lower. Conclusions: It seems that parasitic infections are associated with students’ nutritional status and their parent education.
- ItemEffect of Aspirin Consumption on Hematuria and Cardiovascular Complications After Transurethral Resection of Prostate(Brieflands, 2020-12-30) Mohammad Reza Nikoobakht; Farshad Namdari; Hossein Dialameh; Arash Karimi; Shahrokh Karbalaei Saleh; Masoud Khalili; Mohammad Reza Rahimi; Erfan Jelveh MoghadamObjectives: This study aimed to evaluate the effects of aspirin on hematuria and cardiovascular events after transurethral resection of the prostate (TURP). Methods: This case-control study was conducted at Sina hospital, an affiliated hospital of Tehran University of Medical Sciences, in 2018. We assessed 132 patients with benign prostatic hyperplasia (BPH) who underwent TURP in two groups (66 patients in each group). In the first group, aspirin was withdrawn 5 - 7 days before the surgery. In the second group, aspirin was given without discontinuation before the surgery. Both groups were followed for 30 days to be compared regarding hematuria, duration of hospitalization, Hb decline rate, the necessity for blood transfusion, secondary hematuria, duration of Foley catheter fixation, and cardiovascular complications after TURP. Results: The duration of Foley catheter fixation, Hb decline rate, and duration of hospitalization were significantly associated with aspirin consumption (P value < 0.05) while blood transfusion, secondary hematuria, and cardiac complications did not correlate with aspirin usage. Conclusions: Aspirin consumption might be a risk factor for Foley catheter fixation duration, blood loss, and length of hospital stay.
- ItemEffects of Eight-Week Combined (Resistance and Endurance) Training on Serum Levels of Prostate Specific Antigen (PSA), Sex Hormone Binding Globulin (SHBG), and Phosphatase and Tensin Homolog (PTEN) in Men with Prostate Cancer(Brieflands, 2021-12-31) Abbas Jafari; Hamid Arazi; Amirabbas Monazzami; Alireza Ghadian; Kambiz HasrakBackground: Prostate cancer (PC) is the second most prevalent cancer and the sixth cancer leading to death in men worldwide. Objectives: The purpose of this study was to examine the effect of eight weeks of combined training on specific markers of prostate cancer in older adults. Methods: Twenty older adults (62 ± 7 years) with prostate cancer were divided randomly into the control (n = 10) and training (n = 10) groups. The training group performed exercise training in three sessions a week for eight weeks. Resistance training included two sets of 10 repetitions at 60 - 75% of one-repetition maximum, and endurance training contained treadmill running for 20 - 35 min at 60 - 75% of maximum heart rate. Bruce test, one-repetition maximum, and ELISA technique were used respectively to measure the aerobic performance, strength performance, and serum levels of prostate specific antigen (PSA), sex hormone binding globulin (SHBG), phosphatase and tensin homolog (PTEN), and testosterone (TS). A two-way analysis of variance with repeated measures was used to specify the differences. Results: Weight, fat percentage, body mass index (BMI), waist-hip ratio (WHR), glucose, insulin, and PSA were significantly lower in the training group than the control group (P < 0.05). Furthermore, strength performance, aerobic performance, SHBG, TS, and PTEN were significantly higher in the training group than in the control group (P < 0.05). Conclusions: Combined training can have an influential role in physical condition improvement through decreasing the PSA serum level and increasing SHBG, TS, and PETEN serum levels, which helps patients with prostate cancer to be cured.
- ItemA Novel Classification Method Based on Multilayer Perceptron-Artificial Neural Network Technique for Diagnosis of Chronic Kidney Disease(Brieflands, 2020-05-20) Ali Sharifi; Kamal AlizadehBackground: Chronic kidney disease is one of the most common diseases. The early diagnosis of this disease will reduce the length of treatment and decrease high medical costs. In recent years, the use of computer techniques in data mining and intelligent algorithms has accelerated the early diagnosis of this disease. One of the intelligent methods to diagnose this disease is artificial intelligence networks. Objectives: This study aimed to investigate the diagnosis of chronic kidney disease using an artificial intelligence network based on the multilayer perceptron method. Methods: The data of laboratory samples were collected from 140 healthy people and patients with chronic kidney disease. After preprocessing and normalization, the data were given to a multilayer perceptron and the accuracy of disease diagnosis was evaluated. All analyses were performed using MATLAB software. Results: The simulation showed a 98% accuracy of diagnosis using the proposed model. Conclusions: The results of real data suggested that the proposed system was more effective and faster than other methods in the diagnosis of acute kidney disease and it can be used as a physician assistant tool in clinical practice. In addition, it can be a cost-effective method for patients.
- ItemGender Determination Using Mandibular Angle Measurement in Iranian Adult Graphics in a Dental Center(Brieflands, 2021-09-30) Maryam Vasheghani Farahani; Ramin Mashhadi Ismaeeli; Iraj Mirzaii-Dizgah; Mahdi IsazadehBackground: The mandibular bone is affected by age, metabolic activity, and hormonal changes. Objectives: This study aimed to determine the sex determination using the mandibular angle in the adult population of Iran. Methods: This cross-sectional study enrolled 149 patients (73 men and 76 women) referred to the 600 Army Dental Center in 2016. Graphics were obtained from cephalogram and panorex using a Soredex digital device and Pack software to measure mandibular angles. Results: The mean mandibular angle was 122.19 ± 3.89 in men and 124.72 ± 3.24 in women, with a significant difference based on the independent t test (P < 0.05). Conclusions: It seems that the mandibular angle is higher in women than in men.
- ItemCommunity Health Workers: Heroes of Rural Healthcare(Brieflands, 2024-12-31) Rashidat Oluwabukola Owolabi; Shuaibu Suleiman; Ismail Ademiluyi Ogunniran; Abuhuraira Ado MusaThis article does not have an abstract.
- ItemComparing the effects of using Earplugs and eye masks on sleep quality of patients in coronary care unit (CCU)(Brieflands, 2013-06-30) Mansour Arab; Fatemeh Mashayekhi; Hadi Ranjbar; Farokh Abazari; Eshagh DortajBackground: Sleep disturbance depends on factors such as noise and light in cardiac care unit (CCU). It can lead to acute coronary syndrome in some patients. This study was designed to compare the effect of using eye mask and earplugs in improvement of sleep in CCU patients.
- ItemReduction of Complements C3 and C4 in Saliva and Serum of Patients Suffering SARS-CoV-2 Infection(Brieflands, 2023-12-31) Nima Rahimi Petrudi; Iraj Mirzaii-Dizgah; Ali Atashabparvar; Seyyed-Javad Hosseini-ShokouhBackground: The complement system plays a role in chronic immune activation during viral infections. Objectives: This study aimed to evaluate the levels of saliva and serum complements C3 and C4 in coronavirus disease 2019 (COVID-19) patients and healthy individuals. Methods: This cross-sectional study included 36 severe and 22 critical COVID-19 hospitalized patients and 22 healthy individuals. Serum and unstimulated salivary C3 and C4 levels were assessed using the immunoturbidimetric method and analyzed using one-way analysis of variance (ANOVA) with the Student-Newman-Keuls test as a post hoc analysis. Results: Salivary C3 and C4 levels were significantly lower in patients with severe and critical COVID-19 than in healthy individuals. There was no significant difference between the groups infected with severe and critical COVID-19. Serum C3 and C4 levels were lower in critical COVID-19 patients than in healthy individuals; nevertheless, no significant difference was observed between severe COVID-19 patients and healthy individuals. Additionally, serum C4 levels were lower in critical COVID-19 patients than in severe COVID-19 patients. Conclusions: It appears that serum and salivary C3 and C4 levels decrease in patients with COVID-19 infection.
- ItemThe Effect of Immobilization Stress on the Induction of Diabetes Mellitus in Rats(Brieflands, 2016-06-30) Manzar Banoo Shojaeifard; Zahra Vojdani; Saeed Karbaly-doust; Samira MalekzadehPurpose: The present study aimed to investigate the effect of immobilization stress on the induction of diabetes mellitus in rats. Materials and Methods: In this experimental study 30 mature male rats with an average weight of 200-220 gr were randomly divided into three groups of ten each. Group I served as the control while the experiment groups were Group II (10 days) and Groups III (30 days), which were immobilized in restraining cages twice a day for 45 minutes each time. After the last induction of stress period, blood samples were taken. Glucose was analyzed via the glucose oxidase method, and the levels of glucocorticoid and insulin were determined by radio immunoassay. Data were analyzed using the Kruskal-Wallis and Mann-Whitney tests. Results: The results showed that stress could affect the induction of diabetes by increasing blood glucose, insulin, and glucocorticoid; these changes, however, were not statistically significant. Conclusion: Our data showed that immobilization stress causes the induction of diabetes mellitus in rats.
- ItemEffect of Six Months of Using Thermoplastic Polyurethane and Rubber Military Boots on Lower Limb Muscle Activities During Running(Brieflands, 2024-03-31) Milad Piran Hamlabadi; AmirAli JafarnezhadgeroBackground: The age of boots is a significant factor that can impact the risk of injury during daily activities. Conversely, military personnel rely on their footwear to meet the physical demands of their daily professional tasks. Objectives: This study aimed to evaluate how wearing thermoplastic polyurethane (TPU) and rubber military boots for six months affects lower limb muscle activity during running. Methods: Thirty healthy male participants were provided with two new pairs of rubber and TPU military boots and instructed to wear them for six months. Electromyography signals were recorded during a pre-test and after six months while the participants ran at a speed of 3.2 m/s. Statistical analysis was conducted using a two-way ANOVA with repeated measures, with a significance level of 0.05. Results: The results did not show a significant overall effect of "boots" or "time" on muscle activities during running. However, there were significant boot-by-time interactions for muscle activities during different phases of the running cycle. These interactions were observed for the tibialis anterior (P = 0.037, η2p = 0.146), gastrocnemius medialis (P = 0.023, η2p = 0.172), and gluteus medius (P = 0.038, η2p = 0.144) activities during the loading phase, tibialis anterior activity at the mid-stance phase (P = 0.003, η2p = 0.278), and gastrocnemius medialis activity during the push-off phase (P = 0.046, η2p = 0.135). Conclusions: Wearing military boots appears to affect muscle activities, particularly the tibialis anterior, in healthy males. These findings underscore the importance of careful boot selection for running activities. Understanding the reasons behind differences in muscle activity between TPU and rubber military boots can inform further research and the development of specialized footwear tailored to specific operational needs.