Hepatotoxicity After Exposure to Tebuconazole: A Case Report and Brief Review

AuthorShahram Habibzadehen
AuthorAbbas Yazdanboden
AuthorJafar Mohammadshahien
AuthorNasrollah Malekien
AuthorSobhan Ataeien
OrcidShahram Habibzadeh [0000-0003-0509-7369]en
OrcidJafar Mohammadshahi [0000-0001-9862-4118]en
OrcidNasrollah Maleki [0000-0003-1511-7052]en
Issued Date2019-08-06en
AbstractA 48-year-old man was admitted to our hospital with complaints of productive cough, anorexia, and sweating from two weeks ago. Laboratory studies revealed an increased level of liver enzymes. The work-up of serological markers was negative for both infectious and non-infectious causes of hepatitis. He denied smoking, alcohol consumption, occupational exposures, and illicit drug use. Interestingly, he had a history of contact with an antifungal toxin called tebuconazole about 15 days before admission. In toxicological examinations using gas chromatography with a nitrogen-phosphorus detector, the cause of poisoning was revealed to be fungicide tebuconazole. To confirm the causal relationship between toxin and hepatitis, exposure avoidance and repeated testing were considered. Complete recovery was achieved in all clinical symptoms and laboratory findings. We suggest that tebuconazole-induced hepatitis should be considered in farmers exposed to this fungicide.en
DOIhttps://doi.org/10.5812/hepatmon.94548en
KeywordHepatitisen
KeywordTebuconazoleen
KeywordPoisoningen
PublisherBrieflandsen
TitleHepatotoxicity After Exposure to Tebuconazole: A Case Report and Brief Reviewen
TypeCase Reporten

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