A Comparative Study of Diane?35 plus Spironolactone and Diane ?35 Plus Finasteride in Cases of Hirsutism and Acne
| Author | A Kriplani | en |
| Author | J Thulkar | en |
| Author | N Agrawal | en |
| Author | V Kulshrestha | en |
| Author | AC Ammini | en |
| Author | G Kumar | en |
| Issued Date | 2009-10-31 | en |
| Abstract | To compare the efficacy and safety of Diane 35 plus spironolactone and Diane 35 plus finasteride in the treatment of hirsutism and acne. Materials and Methods: A prospective randomized clinical trial was conducted on 120 Indian women with hirsutism. Group I patients were treated with Diane 35 plus spironolactone 100 mg daily and group II patients with Diane 35 plus finasteride 5 mg daily for 12 months. Hirsutism and acne score were graded every 3 months, for 18 months. The basal gonadotropins levels and androgens level were measured before the study. Statistical analysis was done by Student‘s t-test and repeated measure analysis followed by post hoc comparison. Results: Reduction in hirsutism and acne scores assessed every 3 months was significant (p0.05). Conclusion: Diane 35 plus spironolactone and Diane 35 plus finasteride are equally effective and safe in the treatment of hirsutism and acne. For better outcomes, it is recommended that the treatment period be over 12 months. | en |
| DOI | https://doi.org/ | en |
| Keyword | Hirsutism | en |
| Keyword | Treatment | en |
| Keyword | Diane 35 | en |
| Publisher | Brieflands | en |
| Title | A Comparative Study of Diane?35 plus Spironolactone and Diane ?35 Plus Finasteride in Cases of Hirsutism and Acne | en |
| Type | Research Article | en |
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