Determination of the Lipid Profile of Cord Blood in Neonates and its Correlation with Maternal Age in Iran
| Author | Shahla Vaziri Esfarjani | en |
| Author | Elham Iravani | en |
| Author | Maryam Razzaghi Azar | en |
| Orcid | Shahla Vaziri Esfarjani [0000-0003-1814-3168] | en |
| Issued Date | 2013-03-01 | en |
| Abstract | Background: Cardiovascular diseases (CVDs) are the leading cause of mortality in Iran; with dyslipidemia as an important contributing risk factor. Objectives: To assess the early onset of dyslipidemia, our goal was to determine lipids and lipoproteins levels in cord blood and their correlation with maternal age as a first study in Iran. Patients and Methods: This cross sectional study was done on the cord blood of 243 healthy, full-term newborn infants (114 females and 129 males). The blood was sampled from the umbilical cord immediately after a normal delivery. The serum was tested in order to determine the lipid profile including total cholesterol (TC), triglycerides (TG) and high density lipoprotein-cholesterol (HDL-C). Low density-lipoprotein (LDL-C) was computed by Friedewald equation. Results: A statistically significant negative correlation was observed between cord blood HDL-C and maternal age (r = -0.18, P Conclusions: In a current study based on increasing maternal age, the HDL-C level in cord blood was decreased which is an independent risk factor for CVDs in adulthood. | en |
| DOI | https://doi.org/10.17795/compreped-6347 | en |
| Keyword | Lipid | en |
| Keyword | Lipoprotein | en |
| Keyword | Cord blood | en |
| Keyword | Gender | en |
| Keyword | Maternal Age | en |
| Publisher | Brieflands | en |
| Title | Determination of the Lipid Profile of Cord Blood in Neonates and its Correlation with Maternal Age in Iran | en |
| Type | Research Article | en |
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