Effect of addition of Ondansetron or Magnesium to Lidocaine on duration of analgesia of intravenous regional anesthesia in elective upper extremities surgery: comparative study.

Abstract

BackgroundThis study aimed at evaluating and comparing the effect of ondansetron and magnesium added to lidocaine on intravenous regional anesthesia (IVRA) in the surgery of upper extremity.Settings and design?The current randomized, clinical trial was conducted on 45 patients considered as candidates for upper extremities surgery in Qazvin, Iran. The patients were randomly assigned into three groups. Group C only received 3 mg/kg lidocaine, group O lidocaine + 4 mg/kg ondansetron, and group M lidocaine + 7.5 mL magnesium sulfate 20%. Then, the sensory and motor blocks, tourniquet pain, the amount of administered extra fentanyl, pain intensity, and other parameters involved in analgesia were analyzed in the groups using the statistical tests.ResultsThe time for onset of sensory and motor blocks in group M was significantly shorter than the groups C and O (P