Sero-epidemiology and Risk Assessment of Hepatitis E Virus Among Blood Donors in North Lebanon
| Author | Joyce Ghazzawi | en |
| Author | Sara Moubayed | en |
| Author | Sara Khalife | en |
| Orcid | Joyce Ghazzawi [0000-0001-6605-0228] | en |
| Orcid | Sara Moubayed [0000-0003-2775-0437] | en |
| Orcid | Sara Khalife [0000-0001-7326-0477] | en |
| Issued Date | 2022-06-30 | en |
| Abstract | Background: Hepatitis E virus (HEV) is the causative agent of over 50% of acute viral hepatitis cases. The blood transfusion route has emerged as a possible route of transmission of HEV. Objectives: This study aimed to determine the seroprevalence of IgM and IgG anti-HEV among blood donors in North Lebanon and to assess the risk factors associated with its occurrence. Methods: A cross-sectional study was conducted from November to December 2020. Blood samples were collected from 78 healthy blood donors. A standardized questionnaire containing sociodemographic, food consumption, lifestyle, and health-related characteristics, was filled out to assess the risk factors of HEV exposure. Serum samples were tested for IgM and IgG anti-HEV by an enzyme-linked immunosorbent assay (ELISA). Results: The seroprevalence of IgM and IgG anti-HEV antibodies was reported in our study, and it reached 1.09% (1/78) and 12.82% (10/78), respectively. The use of private wells as a drinking source and the travel history to endemic countries have been identified as risk factors for HEV infections (P Conclusions: Our data, support the implementation of HEV antigen screening before blood donation, to reduce the risk of HEV transmission via blood transfusion. | en |
| DOI | https://doi.org/10.5812/archcid-129115 | en |
| Keyword | Hepatitis E Virus | en |
| Keyword | Prevalence | en |
| Keyword | Risk Factors | en |
| Keyword | Blood Donors | en |
| Keyword | Lebanon | en |
| Publisher | Brieflands | en |
| Title | Sero-epidemiology and Risk Assessment of Hepatitis E Virus Among Blood Donors in North Lebanon | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- archcid-17-3-129115.pdf
- Size:
- 110.11 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF