Serum Level of Vitamin D3 and Renal Stone in Children

AuthorShahin Abbaszadehen
AuthorEhsan Shahverdien
AuthorFatemeh Beiraghdaren
AuthorFatemeh Heydarien
AuthorMohammad Ali Najafizadehen
AuthorMohammad Amin Konjedien
AuthorFatemeh Shafizadeh Barmien
AuthorYasaman Vakiloroayaen
Issued Date2018-05-31en
AbstractBackground: Due to high prevalence of vitamin D insufficiency in Iranian children, researchers found a low level of vitamin D among patients with nephrolithiasis. Objectives: Since previous studies showed hyper-vitaminosis D in patients with renal stone, the current study aimed to clarify this paradox. Materials and Methods: In this cross-sectional study, 100 pediatric patients with renal stone referred to Pediatric Urology and Nephrology Clinic of Baqiyatallah Hospital in Tehran, Iran, in 2014 were selected using a simple sampling method. The serum level of vitamin D3 was measured in a laboratory and the correlation between vitamin D3 and other variables were evaluated. Results: One-hundred pediatric patients, 64% male and 36% female, with renal stone were evaluated. The serum level of vitamin D and calcium had no significant difference between male and female patients. Four patients had vitamin D deficiency, 31 patients had vitamin D insufficiency and others had sufficient levels of vitamin D. There was a direct significant correlation between the level of vitamin D and calcium serum level. Family history of renal colic did not affect the serum levels of vitamin D and calcium. The serum level of vitamin D was significantly higher in patients with bilateral renal stone compared to patients with unilateral renal stone. Conclusions: Serum levels of vitamin D in children with urinary stones were low. The level of vitamin D deficiency was significantly correlated with disease severity and serum level of calcium.en
DOIhttps://doi.org/10.5812/compreped.34357en
KeywordRenal Stoneen
KeywordVitamin Den
KeywordCalciumen
KeywordPediatricen
PublisherBrieflandsen
TitleSerum Level of Vitamin D3 and Renal Stone in Childrenen
TypeBrief Reporten

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