Evaluation of immune response of Hepatitis B vaccination in Zahedan infants

Abstract

Hepatitis B vaccination is the best way of prevention of Hepatitis B infection and chronic liver disease as well as hepatocellular carcinoma. Mass vaccination of Hepatitis B in neonate has started in Iran since 1993. So evaluation of vaccination is essential. In this study, seroconvertion of antiHBs evaluated after complete vaccination of Hepatitis in 15-23 month old infants. 324 infants selected randomly from general population of Zahedan. The positivity rate of antiHBs in male, female and total samples was 77%, 80% and 78.4, respectively. This ratio was less than expected, so we suggest further study about this subject.