Effects of oral clonidine as pre-medication on blood pressure in patients under spinal anesthesia

Abstract

We have studied the effect of oral clonidine on Blood Pressure of the Patients under spinal anesthesia. For minor to moderate surgeries at Khatam-ul-anbia Hospital of Zahedan –Iran in 1380(2001). In this double –blinded , prospective , randomized study involving 50 patients who that divided in two 25-patients groups and the first groups reciveved oral clonidine 2 μg/kg drug 90 min prespinal anesthesia and the other group did not resived any drugs. 12% of group 1 patients had diastolic and systolic hypotension but at group 2 , 24% had systolic hypotension and 16% had diastolic hypotension after 10 min interval of spinal anesthesia. But there were no statistical difference between the two groups. Implications: Oral clonidine as premedication has no any effect on the blood pressure following spinal anesthesia, so we can use oral clonidine as premedication for its benefits.