The effects of Cimetidine on the respiratory burst of the rat’s neutrophils

Abstract

Background & Objectives: Neutrophils are the most important member of granulocytes & the first line of host defence against micro-organisms. They kill micro-organisms entering the body by phagocytic activity. One of the important phases of phagocytic activity is respiratory burst which can be effected by different drugs such as cimetidine. In this study the effects of cimetidine on respiratory burst of rat’s neutrophils are described.