Epidemiological Study of Hepatopancreatobiliary Sarcoma in Iran, 2010 - 2014

AuthorAli Tayebien
AuthorFaranak Olamaeianen
AuthorArash Pour Mohammaden
AuthorMilad Gholizadeh Mesgarhaen
AuthorLeila Asef-Kabirien
AuthorFarid Moradianen
AuthorBehrad Seyedesfahanien
AuthorMohammad Esmaeil Akbarien
OrcidAli Tayebi [0000-0003-3164-9649]en
OrcidFaranak Olamaeian [0000-0001-6677-8059]en
OrcidArash Pour Mohammad [0000-0003-3064-4299]en
OrcidLeila Asef-Kabiri [0000-0003-4066-4760]en
OrcidFarid Moradian [0000-0001-9651-4011]en
OrcidMohammad Esmaeil Akbari [0000-0002-9938-3587]en
Issued Date2022-12-31en
AbstractBackground: Hepatopancreatobiliary (HPB) malignancies are a relatively rare but important type of cancer with usually poor prognosis. Prompt diagnosis and treatment are crucial to improving the patient’s outcome. For this issue, acknowledgment of epidemiological characteristics is helpful. Objectives: In this study, the epidemiological characteristics of cases with HPB sarcoma among Iranian patients were assessed. Methods: In this epidemiological study, 133 consecutive cases with HPB sarcoma in Iran from 2010 to 2014 were evaluated, including gallbladder, pancreas, hepatic, pancreatic body and head, and other biliary tumors. Results: Nine gallbladder sarcoma cases were reported between 2010 and 2014, accounting for 6.7% of all HPB sarcoma cases, and leiomyosarcoma was the most common. A total of 16 patients of pancreatic origin were reported during this period, with the highest rate of 6 cases in 2011; in this sarcoma category, malignant type spindle cell tumor was the most common type accounting for 12.5% of all cases. Ninety-five cases of liver sarcomas were reported generally. Non-specified and desmoplastic small round cell tumors were the most common types. Five cases of pancreatic head sarcomas were reported during 2010 - 2013. There was no predominant tumor type. Five cases of pancreatic head sarcoma were reported during 2010 - 2013. There was no dominant tumor type. About the other biliary tract sites, six patients were reported. Gastrointestinal stromal sarcoma was the most common type. Conclusions: Hepatopancreatobiliary sarcoma in the Iranian population generally has diverse types, and there are different patterns according to the age and sex distribution in patients according to the initial location of the tumor and also their pathological subtypes.en
DOIhttps://doi.org/10.5812/ijcm-118444en
KeywordHepatopancreatobiliary Neoplasmen
KeywordMalignancyen
KeywordSarcomaen
KeywordCanceren
KeywordEpidemiologyen
PublisherBrieflandsen
TitleEpidemiological Study of Hepatopancreatobiliary Sarcoma in Iran, 2010 - 2014en
TypeResearch Articleen

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