Frequency of Hepatitis C in Patients with Rheumatoid Arthritis
| Author | Mohammad Javad Ehsani Ardakani | en |
| Author | Alireza Rajaei | en |
| Author | Hamid Mohaghegh Shalmani | en |
| Author | Negin Shahid | en |
| Author | Mohammad Mehdi Emam | en |
| Author | Nahid Mohammadzadeh | en |
| Author | Seyed Javad Mirhassani Moghaddam | en |
| Author | Mohammadreza Zali | en |
| Issued Date | 2009-01-31 | en |
| Abstract | Background: Hepatitis C virus (HCV) infection has been explained as a disease that sometimes present with rheumatic manifestations indistinguishable from rheumatoid arthritis. This study has been performed to evaluate the frequency of hepatitis C virus infection in a group of patients with rheumatoid arthritis. Patients and methods: In this study, during one year, serum samples collected from two hundred consecutive patients with rheumatoid arthritis in all affiliated hospitals of Shaheed Beheshti University, M.C., were examined for anti-HCV antibody and HCV-RNA by ELISA and RT-PCR method, respectively. Using a questionnaire, the frequency of HCV infection, age and sex distribution, duration of rheumatoid arthritis, associated immune mediated disorders and risk factors for hepatitis C virus infection were assessed. Results: A total of 200 patients (M/F=26/174) who were mainly aged 51-70 years were studied. The frequency of HCV was found to be 2% (95%CI: 0.6-7%). All of the infected persons have had a low risk occupation in terms of exposure to the virus and none of them had HCV risk factors. No associated immune mediated disorder was found in HCV infected patients. Conclusion: Our results did not support any contribution of HCV infection in the pathogenesis of rheumatoid arthritis. | en |
| DOI | https://doi.org/ | en |
| Keyword | Hepatitis C | en |
| Keyword | Rheumatoid arthritis | en |
| Keyword | HCV-RNA | en |
| Keyword | RT-PCR | en |
| Publisher | Brieflands | en |
| Title | Frequency of Hepatitis C in Patients with Rheumatoid Arthritis | en |
| Type | Brief Report | en |
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