Effect of acute injection of norharmane on learning and spatial memory in rats

AuthorMohammad Hossein Esmaeilien
AuthorHashem Haghdosten
AuthorMohammad Sofiabadien
AuthorAida Lotfien
AuthorMahshid Najafien
AuthorMona Hasanien
AuthorMaryam Ashoreh Aghababaeien
AuthorRobabeh Amani Gorgien
AuthorFatemeh Mosavien
Issued Date2014-11-30en
AbstractBackground: Although endogenous and exogenous β-Carbolines, which have been found in blood and tobacco, have neurotoxic effects, , some of these compounds have been shown to have a stimulating effect on the dopaminergic system and to increase dopamine levels in hippocampus, leading to  memory improvement. The aim of the present study was to determine the effects of acute injection of norharmane as a benzodiazepine receptor inverse agonist on learning and spatial memory in water maze.en
DOIhttps://doi.org/10.22110/jkums.v18i8.2079en
Keywordβ-Carbolineen
Keywordnorharmaneen
Keywordlearningen
Keywordspatial memoryen
PublisherBrieflandsen
TitleEffect of acute injection of norharmane on learning and spatial memory in ratsen
TypeResearch Articleen

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