Liver and Plasma Nesfatin-1 Responses to 6 Weeks of Treadmill Running With or Without Zizyphus Jujuba Liquid Extraction in Female Rat
| Author | Abbass Ghanbari Niaki | en |
| Author | Fatemeh Mohammadi Joojadeh | en |
| Author | Navabeh Zare Kookandeh | en |
| Author | Safar Najafi | en |
| Author | Mohammad Javad Chaichi | en |
| Author | Fatemeh Rodbari | en |
| Author | Hasan Bayat | en |
| Issued Date | 2013-03-31 | en |
| Abstract | Background: Nesfatin-1 is a protein derived from a precursor molecule of the nucleobindin-2 gene, and acts as an anorexigenic peptide on food intake behavior, and its level isinfluenced by nutritional status, food composition [fat and carbohydrate (CHO)], and physical exercise. Objectives: The aim of this study was to investigate the effects of 6 weeks of treadmill running (at high intensity) program with and without zizyphus jujuba (high carbohydrate content) crud extraction on liver nesfatin-1, ATP, glycogen, and its plasma concentrations in female rats. Materials and Methods: Twenty-eight Wistar female rats (6-8 weeks old100-120 g of weight) were randomly assigned to saline-control (SC), saline-training (ST), zizyphus jujuba-control (ZJC), and zizyphus jujuba-training (ZJT) groups. Rats ran on a motor-driven treadmill at 35 m/min, 60 min/day, 5 days/week for 6 weeks. Animals received ZJ extraction and saline at the dose of 1.25mL/100g of body weight. Seventy-two hours after the last training session rats were killed, a portion of liver excited, and plasma was collected for nesfatin-1, ATP, and glycogen measurements. A one-way ANOVA method, and Pearson correlation were employed. P < 0.05 was considered as significant. Results: A higher and significant liver nesfatin-1 level was found in ZJ groups (p < 0.005), but plasma nesfatin-1 responded differently. Changes in liver nesfatin-1 were accompanied with an increase in liver glycogen,but not ATP contents. Conclusions: The Findings indicate that higher liver nesfatin-1 and glycogen content by ZJ extraction might be due to the ZJ high CHO content, and it could be consideredas an anti-appetite herb. | en |
| DOI | https://doi.org/10.5812/ijem.8438 | en |
| Keyword | Endurance Training | en |
| Keyword | Nesfatin-1 | en |
| Keyword | Zizyphus Jujuba | en |
| Publisher | Brieflands | en |
| Title | Liver and Plasma Nesfatin-1 Responses to 6 Weeks of Treadmill Running With or Without Zizyphus Jujuba Liquid Extraction in Female Rat | en |
| Type | Research Article | en |
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