Role of Gluten-Free Diet on HbA1c Level in Children with Type 1 Diabetes Mellitus and Celiac Disease
| Author | Hedieh Saneifard | en |
| Author | Ali Sheikhy | en |
| Author | Aida Fallahzadeh | en |
| Author | Marjan Shakiba | en |
| Author | Maryam Kazemi Aghdam | en |
| Author | Asieh Mosallanejad | en |
| Orcid | Hedieh Saneifard [0000-0002-7926-0598] | en |
| Orcid | Marjan Shakiba [0000-0003-3884-5466] | en |
| Orcid | Maryam Kazemi Aghdam [0000-0001-9948-417X] | en |
| Orcid | Asieh Mosallanejad [0000-0001-7926-8218] | en |
| Issued Date | 2024-07-31 | en |
| Abstract | Background: Due to autoimmune mechanisms, celiac disease (CD) may affect patients with type 1 diabetes mellitus (T1DM) more than the general population. Objectives: We evaluated the effect of a gluten-free diet (GFD) on HbA1c levels in patients with both type 1 diabetes and CD. Methods: In this cross-sectional study, biochemical and clinical information was gathered from 174 children with T1DM from January 2013 to January 2019. Results: We assessed 174 children with T1DM (93 girls and 81 boys). Celiac disease was diagnosed in 18 out of 174 cases (10.34%). Height and weight percentiles showed significant differences between children with CD and those without CD (P = 0.015 and P = 0.026, respectively). The average HbA1c in the celiac group was 8.61 ± 2.20 (95% CI: 5.1 - 12.1) prior to GFD therapy. HbA1c was assessed six and twelve months following the initiation of the GFD and was found to be 8.32 ± 1.46 (95% CI: 6 - 9.8) and 8.37 ± 1.67 (95% CI: 6.1 - 10.2), respectively. No significant change in HbA1c was observed before and after therapy (P = 0.501). Conclusions: Diabetic children with CD exhibit lower weight and height compared to those without CD. Gluten-free diet therapy in patients with CD did not affect HbA1c levels. | en |
| DOI | https://doi.org/10.5812/ijem-144736 | en |
| Keyword | Diabetes Mellitus Type 1 | en |
| Keyword | Celiac Disease | en |
| Keyword | HbA1c | en |
| Keyword | Anthropometric | en |
| Publisher | Brieflands | en |
| Title | Role of Gluten-Free Diet on HbA1c Level in Children with Type 1 Diabetes Mellitus and Celiac Disease | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ijem-22-3-144736-publish-pdf.pdf
- Size:
- 243.19 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF