Preparation and Biological Activity of New Collagen Composites Part II: Collagen/Reduced Graphene Oxide Composites
| Author | Todorka G Vladkova | en |
| Author | Iliana A Ivanova | en |
| Author | Anna D Staneva | en |
| Author | Madalina G Albu | en |
| Author | Ahmed S A Shalaby | en |
| Author | Tanya I Topousova | en |
| Author | Anelia S Kostadinova | en |
| Issued Date | 2017-04-30 | en |
| Abstract | With the idea of exploring the biological activity of some newly synthetized chemical compounds and their combinations for development of novel antimicrobial collagen biomaterials, a serial investigation was initiated, starting with the preparation and biological activity study of Collagen/ZnTiO3 nano-composites. This serial investigation continued with the preparation and biological activity study of new collagen-based composites in which self-prepared reduced graphene oxide (RGO) sheets were included as an antimicrobial agent. The new porous collagen/RGO composites demonstrated specific antimicrobial activity to different types microbial species; well pronounced activity against Gram-positive microorganisms (Listeria innocua and Bacillus cereus, both bacteria with typical chains forming, large size cells, and Candida lusitaniae, fungus with specific micelle organization) and lack of activity against Gram-negative bacteria (Pseudomonas putida, Salmonella enterica, Pseudomonas aeruginosa, and Escherichia coli; all bacteria with small size cells) combined with lack of cytotoxicity to eukaryotic cells. | en |
| DOI | https://doi.org/10.5812/jamm.46406 | en |
| Keyword | Collagen/ RGO Composites | en |
| Keyword | Antibacterial and Antifungal Activity | en |
| Keyword | Cytotoxicity | en |
| Publisher | Brieflands | en |
| Title | Preparation and Biological Activity of New Collagen Composites Part II: Collagen/Reduced Graphene Oxide Composites | en |
| Type | Research Article | en |