Evaluation of Insulin Resistance in Severe Preeclampsia.

Abstract

Introduction:: the cause of preeclampsia has not been precisely understood. One of the reasons, as stated by some, might be resistance to insulin however, the role of insulin resistance in occurrence of preeclampsia has not been proven so far. Hence, the objective of this study is to find out the relationship between insulin resistance and severe preeclampsia. Materials and Methods:: In this case-control study 26 healthy pregnant women and 26 women with severe preeclampsia, for whom termination of pregnancy was concluded, were included. Both groups in terms of age, weight, parity and body mass index (BMI) were identical. Furthermore, FBS level, fasting blood insulin and resistance to insulin at the same laboratory and by similar procedures were evaluated for both groups throughout the study and documented in relevant forms. The data were analyzed by SPSS software and P value Results:: The results showed that the level of FBS was not significantly different in preeclamptic patients and healthy pregnant control (p=0.062). Moreover we found that the levels of fasting insulin was similar within two groups (P=0.80). Conclusion:: In current study no relevant was observed between severe preeclampsia and resistance to insulin.