Dimercaptosuccinic Acid Scan as an Alternative Diagnostic Approach in Vesicoureteric Reflux Disease

Abstract

Background: In vesicoureteral reflux urine passage from bladder into kidney and induce hydronephrosis. Current diagnostic methods are voiding cystourethrography and cystogram radionuclide. Dimercaptosuccinic acid scan is not routinely used in vesicoureteral reflux disease. Objectives: So the aim of this study was evaluation diagnostic efficacy of dimercaptosuccinic acid scan as a alternative dignostic approach for vesicoureteral reflux diagnosis. Methods: This is a case series study that was conducted on children who were under the age of 6 with varying degrees of vesicoureteral reflux or by vesicoureteral reflux indication review and referring to Amir Kabir hospital. Vesicoureteral reflux was diagnosed by voiding cystourethrograms and pediatrician confirmation, in following what dimercaptosuccinic acid scans has done for renal parenchyma evaluation. At the end, grade of vesicoureteral reflux in voiding cystourethrograms was campared to dimercaptosuccinic acid scan results. Results: Dimercaptosuccinic acid scan and voiding cystourethrograms were correlated in high grades of vesicoureteral reflux (P = 0.0001). However, in low grade, there is no significant correlation between two tests (P = 0.4). Conclusions: Dimercaptosuccinic acid scan is an appropriate dignostic approach with lower complications in the diagnosis of high graded vesicoureteral reflux, renal scar, and pyolonephrit.