Creatine Revealed Anticonvulsant Properties on Chemically and Electrically Induced Seizures in Mice

AuthorHamed Shafaroodien
AuthorFarnaz Shahbeken
AuthorMehrdad Faizien
AuthorFarzad Ebrahimien
AuthorLeila Moezien
Issued Date2016-10-31en
AbstractCreatine exerts beneficial effects on a variety of pathologies in which energy metabolism and oxidative stress play an etiological role. Creatine supplements have shown beneficial effects on neurological disorders including Parkinson׳s disease, Huntington›s disease, amyotrophic lateral sclerosis, as well as Alzheimer›s disease and stroke. However, the potential benefits of creatine for patients with convulsive disorders remain poorly defined. While some authors did not suggest any anti- or pro-convulsant roles for creatine treatment, others suggest that creatine may be an anticonvulsant agent. In this study, we investigated the effects of creatine on seizures in mice.en
DOIhttps://doi.org/10.22037/ijpr.2016.1943en
KeywordCreatineen
KeywordSeizureen
KeywordPentylenetetrazoleen
KeywordElectroshocken
KeywordMiceen
PublisherBrieflandsen
TitleCreatine Revealed Anticonvulsant Properties on Chemically and Electrically Induced Seizures in Miceen
TypeOriginal Articleen

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