Creatine Revealed Anticonvulsant Properties on Chemically and Electrically Induced Seizures in Mice
Author | Hamed Shafaroodi | en |
Author | Farnaz Shahbek | en |
Author | Mehrdad Faizi | en |
Author | Farzad Ebrahimi | en |
Author | Leila Moezi | en |
Issued Date | 2016-10-31 | en |
Abstract | Creatine exerts beneficial effects on a variety of pathologies in which energy metabolism and oxidative stress play an etiological role. Creatine supplements have shown beneficial effects on neurological disorders including Parkinson׳s disease, Huntington›s disease, amyotrophic lateral sclerosis, as well as Alzheimer›s disease and stroke. However, the potential benefits of creatine for patients with convulsive disorders remain poorly defined. While some authors did not suggest any anti- or pro-convulsant roles for creatine treatment, others suggest that creatine may be an anticonvulsant agent. In this study, we investigated the effects of creatine on seizures in mice. | en |
DOI | https://doi.org/10.22037/ijpr.2016.1943 | en |
Keyword | Creatine | en |
Keyword | Seizure | en |
Keyword | Pentylenetetrazole | en |
Keyword | Electroshock | en |
Keyword | Mice | en |
Publisher | Brieflands | en |
Title | Creatine Revealed Anticonvulsant Properties on Chemically and Electrically Induced Seizures in Mice | en |
Type | Original Article | en |
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