Neuropsychiatric Manifestations of COVID-19 in Hospitalized Pediatrics: A Multicenter Cross-sectional Study
| Author | Ghazal Zahed | en |
| Author | Parvaneh Karimzadeh | en |
| Author | Lawrence Sagin Wissow | en |
| Author | Soroor Arman | en |
| Author | Marzieh Babaee | en |
| Author | Reza Shervin Badv | en |
| Author | Vahideh Zeinali | en |
| Author | Hadi Zarafshan | en |
| Author | Shahnaz Armin | en |
| Author | Shahram Nasiri | en |
| Author | Narges Hashemi | en |
| Author | Alireza Moayedi | en |
| Author | Collaborating Authors Working Group | en |
| Orcid | Ghazal Zahed [0000-0003-3224-3990] | en |
| Orcid | Parvaneh Karimzadeh [0000-0002-6302-9973] | en |
| Orcid | Marzieh Babaee [0000-0002-5714-7500] | en |
| Orcid | Reza Shervin Badv [0000-0002-7477-4688] | en |
| Orcid | Shahnaz Armin [0000-0002-4993-482X] | en |
| Issued Date | 2023-01-31 | en |
| Abstract | Background: The large proportion of coronavirus disease 2019 (COVID-19) patients has been associated with a large number of neuropsychiatric manifestations. Despite the high prevalence of COVID-19, few studies have examined such manifestations, especially in children and adolescents. Objectives: This study investigated neuropsychiatric manifestations in hospitalized children and adolescents admitted for COVID-19 infection in Iran. Methods: This prospective observational study included admitted children and adolescents (4 - 18 years old) diagnosed with COVID-19 infection, pediatric neurologists, child and adolescent psychiatrists, and infectious disease specialists, and assessed 375 infected patients during August and December 2021. Results: Of the 375 patients, 176 (47%) were female, with a mean age of 9.0 ± 3.39 years. Psychiatric and neurological manifestations were reported in 58 (15.5%) and 58 (15.5%) patients, respectively. The most prevalent psychiatric disorders were separation anxiety disorder (SAD) (5.1%), major depressive disorder (MDD) (3.5%), generalized anxiety disorder (GAD) (2.7%), insomnia (2.4%), and oppositional defiant disorder (ODD) (2.4%). Regarding neurological complications, seizures were the most prevalent (13.1%), followed by encephalitis (1.9%), transverse myelitis (0.3%), acute ischemic stroke (0.3%), and Guillain-Barre syndrome (0.3%). There was no significant relationship between the duration of COVID-19 infection (P = 0.54) and ICU admission (P = 0.44) with the emergence of psychiatric symptoms. Conclusions: The most prevalent neurologic and psychiatric complications among children and adolescents with COVID-19 infection were seizures and the symptoms of anxiety/mood disorders, respectively. | en |
| DOI | https://doi.org/10.5812/apid-131511 | en |
| Keyword | Neuropsychiatric Complication | en |
| Keyword | COVID-19 | en |
| Keyword | Child | en |
| Keyword | Adolescent | en |
| Keyword | Seizure | en |
| Keyword | Anxiety Disorder | en |
| Publisher | Brieflands | en |
| Title | Neuropsychiatric Manifestations of COVID-19 in Hospitalized Pediatrics: A Multicenter Cross-sectional Study | en |
| Type | Research Article | en |
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