Antitussive Effect of Rosa damascena in Guinea pigs
| Author | Mohammad Nasser Shafei | en |
| Author | Hassan Rakhshandah | en |
| Author | Mohammad Nasser Shafei | en |
| Issued Date | 2003-10-31 | en |
| Abstract | Several therapeutic effects including hypnotic, antispasmodic, treatment of abdominal andchest pain and strengthening the heart have been described for the flowers of Rosa damascena.North American Indian tribes use a decoction of the roots obtained from the Rosa damascenaplant as a cough remedy and to treat eye problem. Therefore, in the present study the antitussiveeffect of this plant in guinea pigs was evaluated. The antitussive effect of aerosols of two differ-ent concentrations of ethanolic extract (5 and10% w/v), aqueous extract (10 and 20% w/v),codeine, and saline were tested counting the number of cough produced due to aerosol of citricacid 10 min after exposing animal to aerosols of different solutions (n=6 for each solution). Theresults showed a significant reduction in the number of coughs obtained in the presence of bothconcentrations of ethanolic extract, higher co ncentrations of aqueous extract and codeine(P | en |
| DOI | https://doi.org/10.22037/ijpr.2010.61 | en |
| Keyword | Rosa damascena | en |
| Keyword | antitussive effect | en |
| Keyword | Guinea pig | en |
| Keyword | Citric acid | en |
| Keyword | codeine | en |
| Publisher | Brieflands | en |
| Title | Antitussive Effect of Rosa damascena in Guinea pigs | en |
| Type | Research Article | en |
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