Effect of vitamin D supplementation on symptoms and C - reactive protein among patients with migraine
| Author | Tayebeh Mottaghi | en |
| Author | Fariborz Khorvash | en |
| Author | Gholamreza Askari | en |
| Author | Mohammad reza Maracy | en |
| Author | Reza Ghiasvand | en |
| Issued Date | 2015-03-30 | en |
| Abstract | Introduction : Migraine is the most common form of headache around the world including Iran. In recent years, particular notice has been made to the relationship between vitamin D and migraine. Therefore, the purpose of the current study is to investigate the relationship between serum vitamin D levels and CRP and migraine symptoms in patients . Materials and Methods: This study was carried out as a randomized, double-blind clinical trial. Patients were randomly assigned for either intervention or control groups. Patients consumed a vitamin D supplement or placebo (50000 IU/ week) during 10 weeks. Before and after the intervention, serum levels of vitamin D and CRP were measured and migraine symptoms were assessed. To assess the effect of vitamin D supplements on migraine symptoms including severity, duration, frequency of headache attacks and headache diary result (HDR), multivariate and uni-variate analysis of covarients were used as statistical methods of analysis. Results : Significant differences were observed in mean headache frequency and diary result (HDR) between the two groups (P=0.06 and P=0.04) . However, the difference in mean migraine frequencies between the groups displayed a significance threshold (P=0.06). The relationship between migraine headaches and C - reactive protein (CRP) was not determined. Conclusion: the outcome of this study suggests that vitamin D supplements are effective in reducing migraine symptoms including frequency of headache attacks and headache diary result in patients. | en |
| DOI | https://doi.org/ | en |
| Keyword | Vitamin D | en |
| Keyword | Migraine disorders | en |
| Keyword | C-Reactive Protein | en |
| Keyword | ویتامین D | en |
| Keyword | اختلالات میگرن | en |
| Keyword | پروتئین واکنشی c | en |
| Publisher | Brieflands | en |
| Title | Effect of vitamin D supplementation on symptoms and C - reactive protein among patients with migraine | en |
| Type | Research Article | en |