Serum Adropin Level Correlation with Blood Pressure: A case-control study

Abstract

Background: Hypertension is considered a fundamental health issue globally, and adropin is a vascular endothelial protection factor. The increasing prevalence of Hypertension (HTN); i.e., 20 - 50%, among adult populations in developed countries is one of the most common causes of Cardiovascular Diseases (CVDs). HTN is also the major modifiable risk factor for stroke (both ischemic and hemorrhagic). Adropin has the potential to protect the endothelium by increasing the expression of Nitric Oxide (NO) synthesis in the endothelium. Nonetheless, few studies have been conducted on the role of adropin in regulating blood pressure.