COVID-19 Serological Status in Beta-thalassemia Patients in Iran: A Retrospective Descriptive Study
| Author | Shahla Ansari Damavandi | en |
| Author | Shirin Sayyahfar | en |
| Author | Neda Ashayeri | en |
| Author | Maryam Shamspour | en |
| Author | Masoumeh Jafari | en |
| Author | Sarvenaz Salahi | en |
| Issued Date | 2023-11-30 | en |
| Abstract | Background: Patients with beta-thalassemia (BT) are more prone to infections than others, especially when they have some risk factors. Some reports showed the lower severity of Coronavirus disease 2019 (COVID-19) infection in this population. Objectives: In this study, we aimed to determine the serological status of COVID-19 in BT patients. Methods: This cross-sectional study was conducted in September 2020-February 2021 at Ali-Asghar Children's Hospital, Iran. All major and intermedia β-thalassemia patients dependent on blood transfusion were enrolled in this study. Demographic information, including age, gender, thalassemia type, history of splenectomy, and blood type, were recorded in a checklist. Moreover, the patients were asked about their exposure to COVID-19, and the related symptoms, such as cough, fever, headache, and anosmia, in the last six months. The enrolled cases were examined for anti-COVID-19 IgM and IgG to determine the serological status against this virus. Results: The positive IgG and IgM tests against COVID-19 were in 35.7% (25/70) and 20% (14/70) of cases, respectively, while 42.9% (30/70) were either IgM- or IgG-positive. Among the serologically positive cases, six had a history of at least one symptom suspicious of COVID-19. These six included one fever, two coughs, one anosmia, one dyspnea, and one cough and anosmia. Only one of the patients was hospitalized (1%) with fever and dyspnea. No Intensive Care Unit admission or mortality was reported. Conclusions: It seems that COVID-19 is more likely to be mild or asymptomatic in patients with BT. | en |
| DOI | https://doi.org/10.5812/compreped-133639 | en |
| Keyword | Beta-thalassemia | en |
| Keyword | Coronavirus Infection | en |
| Keyword | Serology | en |
| Publisher | Brieflands | en |
| Title | COVID-19 Serological Status in Beta-thalassemia Patients in Iran: A Retrospective Descriptive Study | en |
| Type | Research Article | en |
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