Interstitial Lung Disease in a Patient with Chronic Granulomatous Disease

AuthorNima Rezaeien
AuthorSara Kashefen
AuthorMozhgan Moghtaderien
Issued Date2012-03-31en
AbstractBackground: Chronic granulomatous disease (CGD) is an inherited phagocytes defect, characterized by defects of NADPH-oxidase and inability of bacterial killing, which leads to recurrent life-threatening infections. Respiratory problems, which are the major cause of morbidity in CGD, usually result from recurrent severe infections; however, vigorous inflammatory response could also cause respiratory diseases. Case Presentation: Herein, an 11 year-old patient with CGD is presented who suffered from chronic cough and dyspnea for 7 years. Considering the results of chest X-ray, high-resolution computed tomography, and pulmonary function test, the diagnosis of interstitial lung disease was made. Conclusion: Early recognition of manifestations associated with CGD and appropriate treatment could prevent further complications and reduce morbidity and mortality in this group of patients.en
DOIhttps://doi.org/en
KeywordChronic Granulomatous Diseaseen
KeywordInterstitial Lung Diseaseen
KeywordImmunodeficiencyen
PublisherBrieflandsen
TitleInterstitial Lung Disease in a Patient with Chronic Granulomatous Diseaseen
TypeCase Reporten

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