Invasive Carcinoma Arising in Microglandular Adenosis of the Breast: A Case Report and Literature Review

Abstract

Microglandular adenosis is an uncommon, benign breast disease considered to be a variant of adenosis. Breast carcinoma arising in microglandular adenosis has been reported. Because of its extreme rarity, its clinical and radiological features are not well known. We present a case of invasive carcinoma arising in microglandular adenosis of the breast in a 63-year-old woman with radiologic and pathologic findings. To our knowledge, this is the first case report with breast magnetic resonance imaging findings that shows the wide spectrum of the disease. Microglandular adenosis is important because it mimics carcinoma clinically and pathologically and breast carcinoma can arise in microglandular adenosis. When a core needle biopsy shows microglandular adenosis, complete excision should be considered to rule out the possibility of an associated carcinoma.