A case series report of Iranian children Hemophagocytic Lymphohistiocytosis syndrome

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and potentially life-threatening disease and has to be considered in the differential diagnosis of many conditions. HLH comprises two different conditions that are difficult to differentiate; Familial hemophagocytic lymphohistiocytosis (FHLH) or familial erythrophagocytic lymphohistiocytosis (FEL), and Secondary hemophagocytic syndromes (secondary HLH, sHLH). Herein, we report a case series of Iranian children with HLH and describe the symptoms and outcome of this disease in Iran.