Evaluate the Anti-Fungal Effects of <i>Zataria multiflora</i> Extract on <i>Candida albicans</i> Isolated from Patients in Zabol

Abstract

Background: The overgrowing resistance of the species of candida toward anti-fungus drugs has necessitated the use of compounds with antifungal features. Some plants have antimicrobial features due to their polyphenols components. This paper aims at exploring the anti-fungus effects of Zataria multiflora against Candida albicans. Methods: A total of 20 g of the dried and pounded leaves of the Zataria multiflora was used and its extract was prepared in the rotary device. Various concentrations of all extracts were prepared in the 96 cell microplate. MIC and diameter of the inhibitory shield were measured by dilution method and agar disk, respectively. Results: The Zataria multiflora extract showed good antifungal effects against Candida albicans sample. Therefore, this plant extract can replace chemical drugs and be used against candida-caused infection upon completion of this research trend. Conclusions: In the present study the principles of the extract, different methods of minimum inhibitory concentration (MIC), and mode of action of the extract are discussed.