Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of <i>Vernonia amygdalina </i>Leaf Extracts with Different Methods of Drying
| Author | Oluwaseun Ruth Alara | en |
| Author | Nour Hamid Abdurahman | en |
| Author | Siti Kholijah Abdul Mudalip | en |
| Author | Olusegun Abayomi Olalere | en |
| Orcid | Olusegun Abayomi Olalere [0000-0002-4382-7281] | en |
| Issued Date | 2018-12-09 | en |
| Abstract | Vernonia amygdalina leaf has a significant importance in food and traditional medicine. It has been reported to possess various pharmacological effects. This study was carried out to investigate the influence of microwave-assisted extraction factors on the extraction from V. amygdalina leaves. The results highlighted that an increase in temperature deteriorated the yields of V. amygdalina leaf. Thus, shade-dried samples gave the highest yields at the irradiation times of 10 and 2 min, microwave power of 500 and 600 W, the temperature of 100 and 80°C, the feed-to-solvent ratio of 1:10, and ethanol concentration of 60% v/v using water and ethanol as the extracting solvents, respectively. Likewise, the antioxidant assay resulted in IC50 values of 260 ± 1.1 µg/mL DPPH and 149.78 ± 0.81 µg/mL ABTS for water and 204 ± 0.92 µg/mL DPPH and 31.17 ± 1.4 µg/mL ABTS for ethanol. Therefore, the synergistic mechanism of mass and heat transfer may be accounted for the accelerated extraction due to microwave energy. | en |
| DOI | https://doi.org/10.5812/jjnpp.57620 | en |
| Keyword | Vernonia amygdalina | en |
| Keyword | Extraction | en |
| Keyword | Yield | en |
| Keyword | Drying | en |
| Keyword | Antioxidant | en |
| Publisher | Brieflands | en |
| Title | Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of <i>Vernonia amygdalina </i>Leaf Extracts with Different Methods of Drying | en |
| Type | Research Article | en |
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