The Effect of Aerobic Training with Vitamin C Supplementation on Myeloperoxidase, Asymmetric Dimethyl Arginine and Blood Pressure in Middle-Age Hypertensive Overweight Men
| Author | Ailin Alishahi | en |
| Author | Kamal Azizbeigi | en |
| Author | Khalid Mohammadzadeh Salamat | en |
| Author | Mozafar Yektayar | en |
| Orcid | Ailin Alishahi [0000-0002-6993-2346] | en |
| Orcid | Kamal Azizbeigi [0000-0002-5963-2323] | en |
| Orcid | Khalid Mohammadzadeh Salamat [0000-0001-6327-0516] | en |
| Orcid | Mozafar Yektayar [0000-0002-4490-6774] | en |
| Issued Date | 2019-11-05 | en |
| Abstract | Background: Cardiovascular diseases such as hypertension are global health concerns. Objectives: The purpose of this study was the effect of intensive aerobic training with vitamin C supplementation on myeloperoxidase (MPO), asymmetric dimethyl arginine (ADMA), and blood pressure (BP) in hypertensive men. Methods: Forty hypertensive men (age: 44.6 ± 3.5 y, body mass index: 28.2 ± 1.2 kg.m-2) volunteered to participate in this study and were randomly divided into four groups of aerobic training with vitamin C (ATV; N = 10), aerobic training with placebo (ATP; N = 10), vitamin C group (VC; N = 10) and control (Con; N = 10). The exercise training consisted of running training, which was done three times a week for 10 weeks, with the intensity of 75% - 85% HR max, and the duration of 20 - 45 minutes. ATP and VC groups consumed daily 500 mg of vitamin C or placebo. Fasting blood samples were measured before the start training protocol and 24 hour after last training sessions to measure MPO and ADMA in the serum. Results: The results of present study showed that ADMA and BP were significantly decreased only in ATV and ATP (P ≤ 0.05). However, MPO did not change significantly (P > 0.05). Also, were seen that no significant difference between ATV and ATP groups (P > 0.05). Conclusions: It can be concluded that, aerobic training caused to decrease of dimethyl arginine, that can be a good strategy for control or decrease of blood pressure in hypertensive subjects, however intensive aerobic training with vitamin C may have better efficacy. | en |
| DOI | https://doi.org/10.5812/jcrps.86843 | en |
| Keyword | Oxidative Stress | en |
| Keyword | Aerobic Training | en |
| Keyword | Hypertension | en |
| Publisher | Brieflands | en |
| Title | The Effect of Aerobic Training with Vitamin C Supplementation on Myeloperoxidase, Asymmetric Dimethyl Arginine and Blood Pressure in Middle-Age Hypertensive Overweight Men | en |
| Type | Research Article | en |
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