Evaluation of Neonatal and Maternal Outcomes in Pregnant Women with COVID-19 in Southern Iran: A Case-Control Study

AuthorMarzieh Davoodien
AuthorHamide Barzegaren
AuthorReza Bahramien
AuthorKhadijeh Sadat Najiben
OrcidMarzieh Davoodi [0000-0002-0381-6908]en
OrcidHamide Barzegar [0000-0003-1114-5937]en
OrcidReza Bahrami [0000-0002-8554-4562]en
OrcidKhadijeh Sadat Najib [0000-0002-0094-0145]en
Issued Date2025-04-30en
AbstractBackground: Pregnant women and their fetuses are considered high-risk populations during pandemics, including coronavirus disease 2019 (COVID-19). Objectives: This study aims to evaluate maternal and neonatal outcomes among pregnant women infected with COVID-19. Methods: This descriptive, analytical, retrospective case-control study included COVID-19-infected pregnant women referred to hospitals affiliated with Shiraz University of Medical Sciences in southern Iran from March 2021 to March 2022. Data were collected using a pre-designed checklist covering demographic information and maternal and neonatal outcomes. Analyses were performed using SPSS version 25, with the significance level set at P < 0.05. Results: Significant differences were observed in maternal and neonatal outcomes for variables such as vaginal bleeding, fetal distress, premature birth, intrauterine death, ICU admission, low birth weight, and NICU admission (P < 0.05). Although neonatal transient tachypnea and pneumonia were more than twice as common in infants of COVID-19-infected mothers compared to controls, these findings were not statistically significant (P > 0.05). Similarly, abnormal lung X-rays, thrombocytopenia, and positive CRP were slightly more frequent in infants born to COVID-19-infected mothers, but these differences did not reach statistical significance (P > 0.05). Conclusions: The study highlights the increased risks of adverse short-term and long-term maternal and neonatal outcomes associated with COVID-19 during pregnancy. Prioritizing pregnancy-specific interventions is crucial in pandemic management to mitigate these risks and improve outcomes for both mothers and their infants.en
DOIhttps://doi.org/10.5812/apid-150381en
KeywordCOVID-19en
KeywordPregnancyen
KeywordMothersen
KeywordNewbornen
KeywordInfanten
PublisherBrieflandsen
TitleEvaluation of Neonatal and Maternal Outcomes in Pregnant Women with COVID-19 in Southern Iran: A Case-Control Studyen
TypeResearch Articleen

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