Diuretic Potential of Whole Plant Extracts of <i>Pergularia daemia</i> (Forsk.)
| Author | Vyas Bhavin | en |
| Author | Vyas Ruchi | en |
| Author | Santani DD | en |
| Issued Date | 2011-10-31 | en |
| Abstract | The whole plant, Pergularia daemia (Family: Asclepediaceae), was extracted with 50% alcohol and a fresh batch of the plant material was successively extracted with petroleum ether, ethyl acetate and n-butanol to determine its diuretic activity. The diuretic activity of the different extracts at a dose of 400 mg/Kg was assessed orally in rats with furosemide as a standard drug using Lipschitzs test. All extracts except the petroleum ether extract showed significant increase (p < 0.001) in urine output. Urinary electrolyte excretion was also affected by the extracts: the alcoholic, ethyl acetate and n-butanol extract caused an increase in the urinary excretion of sodium and potassium ions. These findings suggest that among the mentioned extracts, ethanolic has the maximum diuretic activity followed by n-butanol extract. | en |
| DOI | https://doi.org/10.22037/ijpr.2011.1048 | en |
| Keyword | <i>Daemia extensa</i> | en |
| Keyword | Diuretic activity | en |
| Keyword | Diuretic action | en |
| Keyword | Electrolyte | en |
| Publisher | Brieflands | en |
| Title | Diuretic Potential of Whole Plant Extracts of <i>Pergularia daemia</i> (Forsk.) | en |
| Type | Original Article | en |
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