Neuroprotective Effect of Total and Sequential Extract of <i>Scrophularia striata Boiss</i>. in Rat Cerebellar Granule Neurons Following Glutamate- Induced Neurotoxicity: An <i>In-vitro </i>Study
| Author | Parvin Salavati | en |
| Author | Mina Ramezani | en |
| Author | Hamid R Monsef-Esfahani | en |
| Author | Reza Hajiagha | en |
| Author | Maliheh Parsa | en |
| Author | Shoreh Tavajohi | en |
| Author | Seyed Nasser Ostad | en |
| Issued Date | 2013-04-30 | en |
| Abstract | Neuroprotective effect of the extract from aerial parts of Scrophularia striata Boiss (Scrophulariaceae) was investigated against glutamate-induced neurotoxicity on cultured rat pups Cerebellar Granule Neurons (CGNs). CGNs from 8 days old Sprague-Dawley rat were prepared and cultured. The experiments were performed after 8 days in culture. The plant was collected from the northeastern part (Ruin region) of Iran and air-dried at room temperature. The total extract was prepared with maceration of prepared powder in ethanol 80% for three times. | en |
| DOI | https://doi.org/10.22037/ijpr.2013.1301 | en |
| Keyword | CGNs | en |
| Keyword | Glutamate Neurotoxicity | en |
| Keyword | <i>Scrophularia striata</i> | en |
| Keyword | Neuroprotection | en |
| Publisher | Brieflands | en |
| Title | Neuroprotective Effect of Total and Sequential Extract of <i>Scrophularia striata Boiss</i>. in Rat Cerebellar Granule Neurons Following Glutamate- Induced Neurotoxicity: An <i>In-vitro </i>Study | en |
| Type | Original Article | en |