Atypical Course of Viral Hepatitis A Complicated by Acute Kidney Injury

Abstract

Introduction: Hepatitis A is typically a benign disease; however, in rare instances, it can progress to a fulminant course. One uncommon complication of this disease is acute kidney injury (AKI), which requires clinicians’ awareness for timely diagnosis and treatment. Case Presentation: We describe a clinical case involving a 34-year-old man with severe hepatitis A, who had no comorbid conditions. His condition was complicated by acute hepatic encephalopathy of the first stage and AKI. Notably, there were no provoking factors contributing to the development of AKI. This case underscores the importance of recognizing and treating atypical manifestations of acute hepatitis A promptly. Conclusions: This clinical case highlights the significance of a differential diagnostic approach when AKI emerges as the leading clinical syndrome. It also indicates the need for increased awareness among relevant specialists regarding atypical presentations of acute hepatitis A.