Assessment of Educational Intervention Effects on the Level of Oxidative Stress Parameters and Performance in Oncology Staff
| Author | Afsaneh Riazat | en |
| Author | Mohammad Esmaeil Akbari | en |
| Author | Somayeh Farhang | en |
| Author | Sakineh Rakhshanderou | en |
| Author | Hamidreza Mirzaei | en |
| Author | Payam Azadeh | en |
| Author | Mansour Rezazadeh Azari | en |
| Author | Davoud Panahi | en |
| Orcid | Mohammad Esmaeil Akbari [0000-0002-9938-3587] | en |
| Orcid | Somayeh Farhang [0000-0002-6607-6396] | en |
| Orcid | Davoud Panahi [0000-0002-1620-808X] | en |
| Issued Date | 2021-10-31 | en |
| Abstract | Background: Occupational exposure to antineoplastic drugs causes the production of free radicals and their reaction with macromolecules in the body. Objectives: The present study was conducted to evaluate the effectiveness of the educational intervention by using urinary oxidative stress indices of the oncology staff in Iranian hospitals. Methods: Healthy full-time oncology and pharmacy staff (n = 45) participated in this prospective interventional study. The training of the personnel for proper handling of the antineoplastic drugs was given. During their work shift, their performance was recorded in a checklist. Urinary oxidative stress indices of the staff and scores of their performances were obtained before and after their training. Results: The mean performance score of all oncology staff was statistically higher than after 2 months of educational intervention (P < 0.001). The mean activity levels of Superoxide Dismutase and Catalase enzymes of all oncology staff was statistically lower than after 2 months of educational intervention (P < 0.001). The mean level of Malondialdehyde of all oncology staff was statistically lower than after 2 months of educational intervention (P < 0.05). Conclusions: Educational intervention increased oncology staff performance score and it affected the level of the oxidative stress parameters 2 months after the educational intervention by decreasing the activity of enzymes and the level of malondialdehyde. | en |
| DOI | https://doi.org/10.5812/ijcm.113744 | en |
| Keyword | Biological Monitoring | en |
| Keyword | Oncology Staff | en |
| Keyword | Educational Interventions | en |
| Keyword | Performance | en |
| Keyword | Stress Oxidative | en |
| Publisher | Brieflands | en |
| Title | Assessment of Educational Intervention Effects on the Level of Oxidative Stress Parameters and Performance in Oncology Staff | en |
| Type | Research Article | en |
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