Determination of 18 β-Glycyrrhetinic Acid in Glycyrrhiza glabra L. Extract by HPLC
| Author | Somayeh Esmaeili | en |
| Author | Farzaneh Naghibi | en |
| Author | Mahmoud Mosaddegh | en |
| Author | Nazli Nader | en |
| Issued Date | 2006-04-30 | en |
| Abstract | A high performance liquid chromatography method was studied for determination of 18 β-glycyrrhetinic acid in Glycyrrhiza glabra L. (licorice) extract. The operating condition were C-18 reversed phase column (VP-ODS, (250×4.6 mm, 5 mm)) at room temperature, acetonitril/phosphoric acid (3/1) as mobile phase, at flow rate of 0.6ml/min (0-8min), 0.4ml/min (8-20min) and UV detection at 230 nm. The recoveries were %99.60-%102.81 with relative standard deviation between %0.01-%1.58. The relative standard deviation of the repeatability test was %2.96. The method is simple, rapid, safe, accurate, economical and useful for standardization of the licorice products. | en |
| DOI | https://doi.org/10.22037/ijpr.2010.666 | en |
| Keyword | 18 β-Glycyrrhetinic acid | en |
| Keyword | Glycyrrhiza glabra | en |
| Keyword | High performance liquid chromatography (HPLC) | en |
| Keyword | Thin layer chromatography (TLC) | en |
| Publisher | Brieflands | en |
| Title | Determination of 18 β-Glycyrrhetinic Acid in Glycyrrhiza glabra L. Extract by HPLC | en |
| Type | Research Article | en |
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