Predictors of Compliance to Gluten-Free Diet in Children with Celiac Disease

AuthorMehrab Sayadien
AuthorRamin Niknamen
AuthorNasrin Motazedianen
AuthorSeyed Mohsen Dehghanien
AuthorAmirali Mashhadiaghaen
OrcidMehrab Sayadi [0000-0003-2575-790X]en
OrcidRamin Niknam [0000-0002-2608-8018]en
OrcidNasrin Motazedian [0000-0001-9534-4014]en
OrcidAmirali Mashhadiagha [0000-0002-8953-8979]en
Issued Date2022-06-30en
AbstractBackground: Celiac disease (CD) is a common autoimmune disorder that presents intestinal and extra-intestinal symptoms. It is also associated with cardiovascular diseases and malignancies, and mortality risk. The only way to control the disease is to follow a strict gluten-free diet (GFD) for the rest of life. Objectives: This survey aimed to investigate GFD non-adherence and causes in the pediatric setting. Methods: In this study, 187 children aged between 2.5 to 14 years old with a confirmed diagnosis of CD at least for a year were studied using a questionnaire-based interview in a census study between 2018 to 2019 in a referral center in southern Iran. Results: About 40% of children adhered to a GFD poorly. This group significantly complained of more symptoms than the group with high adherence. Improper access was the most important cause of non-adherence to a GFD. The mean current weight and at the time of diagnosis as well as the mean current BMI and at the time of diagnosis in the non-adherent group were significantly lower than the adherent group. However, IgA anti-transglutaminase antibodies and histopathologic examination did not change remarkably. Furthermore, no significant relationship was found between following a GFD and age, age at the time of diagnosis, gender, and parental educational status. Conclusions: According to our results, inaccessibility, high costs, and lack of food labeling were the primary reasons for non-adherence to GDF. Therefore, to increase compliance, easy access to GFD with proper food labeling and suitable price should be implemented.en
DOIhttps://doi.org/10.5812/ijp-116390en
KeywordCeliac Diseaseen
KeywordComplianceen
KeywordGluten Free Dieten
KeywordChildrenen
KeywordAdolescentsen
PublisherBrieflandsen
TitlePredictors of Compliance to Gluten-Free Diet in Children with Celiac Diseaseen
TypeResearch Articleen

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