Antifungal Effect of the Extract of the Plants Against <i>Candida albicans</i>

Abstract

Background: Medicinal plants are widely used throughout the world. Since these plants are known to have minimal side effects, many people embrace them. This study aims to investigate the antifungal effects of the extracts of the plants against Candida albicans. Methods: The extracts of Echinophora platyloba, Peganum harmala, Heracleum persicum and Rosmarinus officinalis were prepared using a rotary device. The inhibitory concentration against Candida albicans was determined using incubation in media. Results: The results show that highest MIC of R. officinalis against C. albicans was 100 ppm and low MIC was 12.5 ppm against C. albicans (Table 1) and the highest MIC of E. platyloba against C. albicans was 150 ppm and low MIC was 12.5 ppm against C. albicans. The results of this study showed that by increasing the concentration of plant extracts inhibited by the fungus has also been increased. Futhermore, Heracleum persicum extract concentration inhibited growth of fungal ppm 25 while Peganum harmala extract concentration inhibited growth ppm 50. Conclusions: The results showed good antifungal activity Peganum harmala, Echinophora platyloba, Rosmarinus officinalis and Heracleum persicum has expressed Feb plants can be used to treat infections caused by these.