Involvement of the Spinal Cord in the Alzheimer’s Disease: A Literature Review

Abstract

Context: Pathologic studies often show an involvement of the spinal cord in the early stages of the Alzheimer’s (AD) disease; clinical studies further show a statistically-relevant frequency of gait impairment and an increased risk of falling. Therefore, the spinal cord is possibly involved in the Alzheimer’s disease and has a role in the appearance of some symptoms.