Dexmedetomidine Mechanism of Action: an update
| Author | Sara Salarian | en |
| Author | Bahar Taherkhanchi | en |
| Author | Ali Dabbagh | en |
| Author | Mahboubeh Darban | en |
| Author | Bahador Bagheri | en |
| Orcid | Sara Salarian [0000-0002-4544-8883] | en |
| Orcid | Ali Dabbagh [0000-0003-4344-8131] | en |
| Orcid | Bahador Bagheri [0000-0003-2574-8034] | en |
| Issued Date | 2016-06-30 | en |
| Abstract | Dexmedetomidine (PRECEDEX) is an imidazole derivative that is a highly selective a2 receptor agonist. Activation of the a2 adrenergic receptors by dexmedetomidine leads to both sedation and analgesia; with negligible respiratory and cardiovascular side effects. The drug is likely to be increasingly used for sedation and as an anesthetic adjunct. | en |
| DOI | https://doi.org/10.22037/jcma.v1i2.11398 | en |
| Keyword | Dexmedetomidine | en |
| Keyword | neuroprotection | en |
| Keyword | reperfusion injury | en |
| Publisher | Brieflands | en |
| Title | Dexmedetomidine Mechanism of Action: an update | en |
| Type | Review | en |
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