Anemia and Microvascular Complications in Patients With Type 2 Diabetes Mellitus
| Author | Mahboobeh Sadat Hosseini | en |
| Author | Zohreh Rostami | en |
| Author | Alireza Saadat | en |
| Author | Sayyed Mehdi Saadatmand | en |
| Author | Effat Naeimi | en |
| Issued Date | 2014-07-01 | en |
| Abstract | Background: Although chronic kidney disease-induced anemia is more prevalent in patients with diabetes mellitus (DM), anemia is a common finding prior to manifestation of kidney disease. In presence of some risk factors at the time of diagnosing DM, microvascular complications must be considered. The effect of anemia as a risk factor on progression of DM complications is still unclear. Objectives: The aim of the study was to determine the prevalence of anemia and its association with microvascular complications in patients with type 2 DM. Patients and Methods: This cross-sectional study was performed in the outpatient endocrinology clinic at Baqiyatallah University of Medical Sciences Hospital, Tehran, Iran. Study was done from February 2011 to February 2012. Patients with type 2 DM without any obvious symptom or sign of anemia were included in study. Results: A total of 93 patients (30.4%) had anemia including 46 (15.1%) with normochromic normocytic, 44 (14.4%) with hyperchromic microcytic, and 3 (1%) with hyperchromic macrocytic anemias. There was a positive correlation between duration of DM and anemia. Microvascular complications were more frequent with normocytic or microcytic anemias. Glomerular filtration rate (GFR) was higher in patients without anemia; moreover, nephropathy was less frequent among them. Among patients with anemia, 43% had GFR of more than 90 mL/min and 19.4% had normoalbuminuria. Neuropathy, nephropathy, and retinopathy had strong association with anemia (odds ratio of 1.99, 1.7, and 1.5, respectively). Conclusions: Anemia is a common complication of DM and is associated with duration of disease and microvascular complications. | en |
| DOI | https://doi.org/10.5812/numonthly.19976 | en |
| Keyword | Anemia | en |
| Keyword | Diabetes Mellitus | en |
| Keyword | Microvascular Complications | en |
| Publisher | Brieflands | en |
| Title | Anemia and Microvascular Complications in Patients With Type 2 Diabetes Mellitus | en |
| Type | Research Article | en |
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