The Effect of Apple Juice on Antioxidant Enzymes and Lipid Profiles in Orchidectomized Rats
| Author | Mahmood Abedinzade | en |
| Author | Katayoon Harialchi | en |
| Author | Korosh Khanaki | en |
| Author | Mahmood Khosravi | en |
| Author | Mojtaba Farahbakhsh | en |
| Issued Date | 2015-03-28 | en |
| Abstract | Background:: The age-dependent worsening of lipid profiles increased the risk of cardiovascular disease in males. Eating fruits and vegetables is known to be beneficial on lipid profile. Objectives:: The objective of this research was to delineate whether drinking daily squeezed apple juice (AJ) modulates lipid profile and antioxidant enzymes in the animal model that gonadectomized. Materials and Methods:: In this experimental study, 28 male rats were equally divided among the following 4 groups: group I (control), orchidectomized (ORX), ORX +AJ 10%, and ORX+ AJ 25%. After 60 days of drinking AJ, superoxide dismutase (SOD), alkaline phosphatase (ALP), cholesterol, LDL, HDL and triglycerides in serum were evaluated. Data analyzed by SPSS-16 and computed using one way ANOVA followed by Tukey multiple comparison test. P < 0.05 was statistically significant. Results:: In the ORX group compared with the sham group serum SOD and ALP activities decreased (P < 0.05), while serum cholesterol, triglycerides, LDL increased but HDL decreased in ORX groups (P < 0.05). In contrast to the ORX group, drinking AJ decreased (P < 0.05) concentration of LDL, TG and cholesterol in the serum. AJ also increased (P < 0.05) serum HDL, SOD and ALP activities compared with the ORX group. Conclusions:: Drinking AJ prevented oxidative stress by elevating serum antioxidant enzymes. | en |
| DOI | https://doi.org/10.17795/zjrms1132 | en |
| URI | https://brieflands.com/journals/zjrms/articles/1132 | en |
| Keyword | Antioxidants | en |
| Keyword | Cholesterol | en |
| Keyword | Malus | en |
| Keyword | Rats | en |
| Publisher | Brieflands | en |
| Title | The Effect of Apple Juice on Antioxidant Enzymes and Lipid Profiles in Orchidectomized Rats | en |
| Type | Research Article | en |
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