Uranyl Acetate Induces Oxidative Stress and Mitochondrial Membrane Potential Collapse in the Human Dermal Fibroblast Primary Cells
| Author | Bahram Daraie | en |
| Author | Jalal Pourahmad | en |
| Author | Neda Hamidi-Pour | en |
| Author | Mir-Jamal Hosseini | en |
| Author | Fatemeh Shaki | en |
| Author | Masoud Soleimani | en |
| Issued Date | 2012-04-30 | en |
| Abstract | Cytotoxicity of depleted uranium, as a byproduct of military has been came to spotlight in recent decades. DU is known as a chemical rather than radioactive hazard and efforts to illustrating its mechanism is undergo, but the precise complete molecular mechanisms are still unclear. Recent studies showed that uranium induces biological changes in many different target tissues, such as the kidney, brain and skin. The aim of this study was to assess the impact of depleted uranium exposure at the cellular level in the human dermal fibroblast primary cells. The human dermal fibroblast primary cells incubated with different concentration (250-750 μM) of depleted uranium. | en |
| DOI | https://doi.org/10.22037/ijpr.2012.1151 | en |
| Keyword | Uranium | en |
| Keyword | Fibroblast | en |
| Keyword | Lipid peroxidation | en |
| Keyword | Oxidative stress | en |
| Publisher | Brieflands | en |
| Title | Uranyl Acetate Induces Oxidative Stress and Mitochondrial Membrane Potential Collapse in the Human Dermal Fibroblast Primary Cells | en |
| Type | Original Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- IJPR-011-495.pdf
- Size:
- 438.58 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF