Review on Approved and Inprogress COVID-19 Vaccines
| Author | Amir Farnudian-Habibi | en |
| Author | Mobina Mirjani | en |
| Author | Vahideh Montazeri | en |
| Author | Shima Aliebrahimi | en |
| Author | Iman Katouzian | en |
| Author | Saeed Abdolhosseini | en |
| Author | Ali Rahmani | en |
| Author | Hossein Keyvani | en |
| Author | Seyed Nasser Ostad | en |
| Author | Mazda Rad-Malekshahi | en |
| Orcid | Amir Farnudian-Habibi [0000-0002-7889-0889] | en |
| Orcid | Seyed Nasser Ostad [0000-0002-5476-8010] | en |
| Orcid | Mazda Rad-Malekshahi [0000-0002-0329-1320] | en |
| Issued Date | 2022-12-31 | en |
| Abstract | The last generation of Coronavirus named COVID-19 is responsible for the recent worldwide outbreak. Concerning the widespread and quick predominance, there is a critical requirement for designing appropriate vaccines to surmount this grave problem. Correspondingly, in this revision, COVID-19 vaccines (which are being developed until March 29th, 2021) are classified into specific and non-specific categories. Specific vaccines comprise genetic-based vaccines (mRNA, DNA), vector-based, protein/recombinant protein vaccines, inactivated viruses, live-attenuated vaccines, and novel strategies including microneedle arrays (MNAs), and nanoparticles vaccines. Moreover, specific vaccines such as BCG, MRR, and a few other vaccines are considered Non-specific. What is more, according to the significance of Bioinformatic sciences in the cutting-edge vaccine design and rapid outbreak of COVID-19, herein, Bioinformatic principles including reverse vaccinology, epitopes prediction/selection and, their further applications in the design of vaccines are discussed. Last but not least, safety, challenges, advantages, and future prospects of COVID-19 vaccines are highlighted. | en |
| DOI | https://doi.org/10.5812/ijpr.124228 | en |
| Keyword | COVID-19 | en |
| Keyword | Reverse Vaccinology | en |
| Keyword | Bioinformatic | en |
| Keyword | Epitope Prediction | en |
| Keyword | <i>mRNA</i> Vaccine | en |
| Publisher | Brieflands | en |
| Title | Review on Approved and Inprogress COVID-19 Vaccines | en |
| Type | Review Article | en |