Antituberculosis Drug-Induced Hepatotoxicity in IranianTuberculosis Patients: Role of Isoniazid Metabolic Polymorphism
| Author | Mohammad Sistanizad | en |
| Author | Ebrahim Azizi | en |
| Author | Hosein Khalili | en |
| Author | Mahboobeh Hajiabdolbaghi | en |
| Author | Kheirollah Gholami | en |
| Author | Reza Mahjub | en |
| Issued Date | 2011-07-31 | en |
| Abstract | The aim of this study was to determine the association of n-acetyltransferase-2 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in Iranian pulmonary tuberculosis patients. Acetylating phenotypes was studied in 50 Iranian pulmonary tuberculosis patients using metabolic ratio of plasma acetyl-Isoniazid to Isoniazid. The association between hepatotoxicity and the n-acetyltransferase-2 phenotype was evaluated by using the chi-square (x2) test. | en |
| DOI | https://doi.org/10.22037/ijpr.2011.996 | en |
| Keyword | Antituberculosis | en |
| Keyword | Tuberculosis | en |
| Keyword | Polymorphism | en |
| Keyword | Isoniazid | en |
| Keyword | Hepatotoxicity | en |
| Publisher | Brieflands | en |
| Title | Antituberculosis Drug-Induced Hepatotoxicity in IranianTuberculosis Patients: Role of Isoniazid Metabolic Polymorphism | en |
| Type | Original Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ijpr-10-633.pdf
- Size:
- 383.48 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF