Study on the Effect of Paliurus spina-christi on Cholesterol, Triglyceride and HDL Levels in Diabetic Male Rats Fed a High Cholesterol Diet
| Author | Mahmoud Mosaddegh | en |
| Author | Mohammad Javad Khoshnood | en |
| Author | Mohammad Kamalinejad | en |
| Author | Elham Alizadeh | en |
| Issued Date | 2004-01-31 | en |
| Abstract | Paliurus spina-christi Mill (Rhamnaceae) has been used in folk medicine as a hypocholesterolemic agent. In this study, the effect of total fruit extract on lowering lipid content of serum was investigated. Male rats were introduced streptozocin, subsequently fed with a high cholesterol diet and concomitantly treated with various doses of the extract. After 8 days, serum levels of cholesterol, triglyceride and HDL were measured. It was found that the administration of 100 mg/kg/day of the extract had reduced the amount of total cholesterol by 45.5% and the administration of 50 mg/kg/day reduced the amount of triglyceride by 48.73%. No significant enhancement was found in the amount of HDL. It was concluded that of Paliurus spina-christi extract can inhibit the enhancement of cholesterol and triglyceride. | en |
| DOI | https://doi.org/10.22037/ijpr.2010.297 | en |
| Keyword | Paliurus spina-christi | en |
| Keyword | Streptozocin | en |
| Keyword | Triglyceride | en |
| Keyword | Hypercholesterolemia | en |
| Publisher | Brieflands | en |
| Title | Study on the Effect of Paliurus spina-christi on Cholesterol, Triglyceride and HDL Levels in Diabetic Male Rats Fed a High Cholesterol Diet | en |
| Type | Research Article | en |
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