Time-Trend Analysis of Bladder Cancer Incidence in Shahroud and Meyami (2010 - 2022): A Population-Based Registry Study

AuthorNazanin Azmi-Naeien
AuthorZahra Kordien
AuthorMostafa Enayatradeen
AuthorMansooreh Fatehen
AuthorMohammad Hassan Emamianen
OrcidNazanin Azmi-Naei [0000-0001-8778-6314]en
OrcidZahra Kordi [0000-0002-7191-6310]en
OrcidMostafa Enayatrade [0000-0003-3465-3715]en
OrcidMansooreh Fateh [0000-0001-7930-4637]en
OrcidMohammad Hassan Emamian [0000-0002-1994-1105]en
Issued Date2025-12-31en
AbstractBackground: Bladder cancer (BC) is among the ten most common cancers around the world, significantly impacting public health. Objectives: This study aimed to analyze the incidence and trends of BC over 13 years, between 2010 and 2022, in Shahroud and Meyami, Northwest Iran. Methods: The data were collected from the population-based cancer registry system at Shahroud University of Medical Sciences, which includes patients from the Shahroud and Meyami districts. The crude and age-standardized incidence rates (ASRs) for BC were calculated based on age and sex using the direct standardization method with the World Standard Population. The annual percentage change (APC) and the average annual percentage change (AAPC) were reported using Joinpoint regression models. Results: A total of 298 BC cases were recorded between 2010 and 2022, with the majority of patients being men (241 cases, 80.9%). The mean age of participants was 64.6 ± 14.6. The highest number of reported cases occurred in 2021, with a total of 33 cases documented. The ASR increased from 4.9 [95% confidence interval (CI): 2.0 - 7.8] to 12.2 (95% CI: 7.8 - 16.6) during 13 years. Similarly, this pattern was observed in men, with an increase from 7.9 (95% CI: 2.7 - 13.1) to 23.8 (95% CI: 14.5 - 31.6) while the rate for women remained stable, with no statistically significant change, ranging from 1.8 (95% CI: 0.0 - 4.3) to 1.4 (95% CI: 0.0 - 3.3). For the whole period, the total APC was 4.7% (95% CI: 1.3 - 9.0). Conclusions: Over the observed period, there was a consistent increase in the incidence rate of BC among men in Shahroud and Meyami, but it remained constant among women.en
DOIhttps://doi.org/10.5812/ijcm-165328en
KeywordBladder Canceren
KeywordAge-Standardized Incidence Rateen
KeywordJoinpoint Analysisen
KeywordIranen
PublisherBrieflandsen
TitleTime-Trend Analysis of Bladder Cancer Incidence in Shahroud and Meyami (2010 - 2022): A Population-Based Registry Studyen
TypeResearch Articleen

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