Comparison of Characteristics and Outcomes of Hepatitis B and Hepatitis C Patients in the Fars Hepatitis Registry
| Author | Ali Reza Safarpour | en |
| Author | Sara Shojaei-Zarghani | en |
| Author | Leila Rahmati | en |
| Author | Yousef Nikmanesh | en |
| Author | Gholam Reza Sivandzadeh | en |
| Author | Lida Ahmadi | en |
| Author | Saeid Amirizadeh | en |
| Author | Mohammad Reza Fattahi | en |
| Orcid | Ali Reza Safarpour [0000-0002-9880-0043] | en |
| Orcid | Gholam Reza Sivandzadeh [0000-0001-5461-5754] | en |
| Orcid | Saeid Amirizadeh [0000-0003-2347-5204] | en |
| Issued Date | 2024-12-31 | en |
| Abstract | Background: Hepatitis, which refers to liver inflammation, can have various causes, with viral hepatitis being the most common. Objectives: This study aimed to compare demographic and laboratory variables, risk factors, and outcomes between Hepatitis B (HBV) and Hepatitis C (HCV) patients in the Fars hepatitis registry. Methods: In this cross-sectional study, a total of 6,690 eligible patients, consisting of 3,840 (57.4%) with HBV and 2,820 (42.6%) with HCV, were assessed from the database covering the period from 1995 to 2023. Comparisons between HBV and HCV were made using the Chi-square test, Fisher's exact test, or independent sample t-test with SPSS software. Results: The average age of the patients was 52.56 years (standard deviation: 13.24). Significant differences were found between HBV and HCV patients regarding sex, marital status, education level, family history of HBV and HCV, smoking status, drug use, and body mass index (P < 0.001 for all). Hepatitis B patients had a higher prevalence of dental procedures (P < 0.001) and uncertain sexual contacts (P = 0.009), while blood transfusion, intravenous drug use, major thalassemia (P < 0.001 for all), tattoos (P = 0.004), and hemodialysis (P = 0.001) were more common in HCV patients. Hepatitis C patients showed higher levels of liver enzymes (P < 0.001) and total bilirubin (P = 0.002) but lower levels of albumin (P < 0.001) and prothrombin time (P = 0.034) compared to HBV patients. Cirrhosis was also more common in HCV patients (P < 0.001). Conclusions: Our findings highlight different patterns of demographic factors, risk factors, and outcomes between HBV and HCV patients, which could influence their prevention and management strategies. | en |
| DOI | https://doi.org/10.5812/hepatmon-150623 | en |
| Keyword | Hepatitis B Virus | en |
| Keyword | Hepatitis C Virus | en |
| Keyword | Registries | en |
| Keyword | Risk Factors | en |
| Publisher | Brieflands | en |
| Title | Comparison of Characteristics and Outcomes of Hepatitis B and Hepatitis C Patients in the Fars Hepatitis Registry | en |
| Type | Research Article | en |
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