The Fertility Outcome of Royal Jelly versus Intra Uterine Insemination: A Pilot Randomized Controlled Trial Study

AuthorTahereh Fathi Najafien
AuthorNayereh Khademen
AuthorNarjes Bahrien
AuthorMojtaba Meshkaten
AuthorShirin Sadrien
AuthorSareh Dashtien
OrcidTahereh Fathi Najafi [0000-0003-0280-5980]en
OrcidNayereh Khadem [0000-0001-9652-1166]en
OrcidNarjes Bahri [0000-0002-1877-2573]en
OrcidMojtaba Meshkat [0000-0003-0507-3295]en
OrcidShirin Sadri [0000-0002-3751-6444]en
OrcidSareh Dashti [0000-0003-2145-4290]en
Issued Date2021-08-31en
AbstractBackground: The popularity of complementary and alternative medicine is on the rise. Objectives: The current study aimed to compare the effect of vaginal royal jelly with intrauterine insemination (IUI) on sub-fertility in men. Methods: The sample size was estimated as 27 subjects, based on a study power and confidence interval of 80% and 95%, respectively. The study was conducted in Mashhad, in the Northeast of Iran, from 2015 to 2017. Men with sub-fertility (asthenozoospermia, defined as total sperm motility below 40% and sperm concentration below 20 million/mL), with healthy wives, based on salpingography, participated in this study. Patients were assigned to the royal jelly group, which received 5 grams of royal jelly, and the IUI group, which received 75 units of Follicle Stimulating Hormone (FSH) from the second day of the menstrual cycle. Semen samples were collected in sterile plastic caps after 72 hours of sexual abstinence by normal sexual intercourse. Samples were prepared using the standard swim-up technique. Results: This study showed no significant difference between groups concerning spousal age, occupation, education (husband and wife), and social class (P = 0.745). Also, no significant difference was found between groups concerning fertility success rate (P = 0.573). Conclusions: Based on similar treatment success rates of royal jelly and IUI, it seems that royal jelly can be considered as an alternative to IUI.en
DOIhttps://doi.org/10.5812/jjnpp.107420en
KeywordRoyal Jellyen
KeywordInfertilityen
KeywordIntra Uterine Inseminationen
KeywordMale Infertilityen
KeywordClinical Trialen
KeywordSub-Fertilityen
PublisherBrieflandsen
TitleThe Fertility Outcome of Royal Jelly versus Intra Uterine Insemination: A Pilot Randomized Controlled Trial Studyen
TypeResearch Articleen

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